SCHEMBL6827448

SCHEMBL6827448

[CH2]C(=O)C(C)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6646702 0.75
SCHEMBL272583 0.75
Ethylene SCHEMBL11225868 0.74
SCHEMBL3910041 0.72
SCHEMBL1066789 0.72
SCHEMBL852065 0.72
SCHEMBL11149667 0.72 ALDH1A1 (0.39)
SCHEMBL1567548 0.72
SCHEMBL4650548 0.72
SCHEMBL50227 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117164499-A Substituted benzofurans, benzopyrroles, benzothiophenes and structurally related complement inhibitors 拜奥克里斯特制药公司 2023-12-05 CN disclosed
CN-117015542-A Process for preparing pyrrolopyridine derivatives ST制药株式会社 2023-11-07 CN disclosed
CN-112272553-B Substituted benzofurans, benzopyrroles, benzothiophenes and structurally related complement inhibitors 拜奥克里斯特制药公司 2023-09-22 CN disclosed
CN-112794860-B Oxazole pyrimidone amide compound or medicinal salt thereof, preparation method and application 上海肇钰医药科技有限公司 2021-06-29 CN disclosed
CN-112794860-A Oxazole pyrimidone amide compound or medicinal salt thereof, preparation method and application 上海肇钰医药科技有限公司 2021-05-14 CN disclosed
CN-1531527-A Carbazole derivatives and their use as neuropeptide Y5 receptor ligands 2004-09-22 CN disclosed
US-20040067999-A1 Carbazole derivatives and their use as neuropeptide y5 receptor ligands ASTRAZENECA AB (SE) 2004-04-08 US disclosed
EP-1358157-A1 CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS AstraZeneca AB (SE) 2003-11-05 EP disclosed
WO-2002051806-A1 CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS ASTRAZENECA AB (SE) 2002-07-04 WO disclosed
EP-0344660-B1 THIOPHENE DERIVATIVES BASF Aktiengesellschaft (DE) 1992-07-22 EP disclosed
EP-0400618-A2 Textile lubrication ETHYL CORPORATION (US) 1990-12-05 EP disclosed
US-4937256-A Herbicides BASF AKTIENGESELLSCHAFT (DE) 1990-06-26 US disclosed
US-4932976-A Textile lubrication ETHYL CORPORATION (US) 1990-06-12 US disclosed
EP-0344660-A1 Thiophene derivatives BASF Aktiengesellschaft (DE) 1989-12-06 EP disclosed