Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8132063 | 0.82 | — | — | |
| SCHEMBL14785538 | 0.82 | — | — | |
| SCHEMBL27896 | 0.82 | — | — | |
| SCHEMBL7873745 | 0.78 | ALDH1A1 (0.33) | TSHRALDH1A1LMNACYP2E1 | |
| Ammonia Solution, Strong SCHEMBL9376245 | 0.76 | — | — | |
| Trichloromonofluoromethane SCHEMBL11596028 | 0.76 | TSHR (0.38) | TSHRALDH1A1LMNACYP2E1 | |
| Dichlorodifluoromethane SCHEMBL9065291 | 0.76 | TSHR (0.38) | TSHRALDH1A1LMNACYP2E1 | |
| SCHEMBL29996627 | 0.76 | — | — | |
| Benzene SCHEMBL504705 | 0.76 | TSHR (0.57) | TSHRALDH1A1TP53LMNACYP2E1 | |
| SCHEMBL28869301 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1482940-A2 | PRODRUGS OF SUBSTITUTED POLYCYCLIC COMPOUNDS USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | Pharmacia Corporation (US) | 2004-12-08 | — | — | EP | disclosed |
| WO-2003028729-A2 | PRODRUGS OF SUBSTITUTED POLYCYCLIC COMPOUNDS USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | PHARMACIA CORPORATION (US) | 2003-04-10 | — | — | WO | disclosed |