⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL6987367 | 0.96 | — | — | |
| SCHEMBL3200602 | 0.74 | — | — | |
| SCHEMBL4611226 | 0.72 | CA5A (0.43) | — | |
| SCHEMBL31588603 | 0.72 | CA5A (0.43) | — | |
| SCHEMBL16114314 | 0.72 | — | — | |
| SCHEMBL321132 | 0.72 | — | — | |
| SCHEMBL1558758 | 0.72 | — | — | |
| SCHEMBL18474504 | 0.72 | — | — | |
| SCHEMBL4559087 | 0.69 | — | — | |
| SCHEMBL272738 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040106635-A1 | having small-conductance potassium channel (SK) blocking activity | TANABE SEIYAKU CO., LTD. (JP) | 2004-06-03 | — | — | US | claimed |
| EP-1373247-A2 | SPIROISOQUINOLINE COMPOUNDS, METHODS FOR THEIR PREPARATION AND INTERMEDIATES THEREOF | TANABE SEIYAKU CO., LTD. (JP) | 2004-01-02 | — | — | EP | claimed |
| WO-2002079189-A2 | SPIROISOQUINOLINE COMPOUNDS, METHODS FOR THEIR PREPARATION AND INTERMEDIATES | TANABE SEIYAKU CO., LTD. (JP) | 2002-10-10 | — | — | WO | claimed |
| EP-0934303-A2 | COMPOUNDS USEFUL FOR INHIBITION OF FARNESYL PROTEIN TRANSFERASE | SCHERING CORPORATION (US) | 1999-08-11 | — | — | EP | claimed |
| WO-1998011091-A2 | TRICYCLIC COMPOUNDS USEFUL FOR INHIBITION OF FARNESYL PROTEIN TRANSFERASE | SCHERING CORPORATION (US) | 1998-03-19 | — | — | WO | claimed |
| EP-0466733-A1 | PREPARATION OF SUBSTITUTED ETHENES. | FINE ORGANICS LTD (GB) | 1992-01-22 | — | — | EP | claimed |
| CN-217809227-U | Nizatidine synthesis and refining equipment combination | 无棣融川医药化工科技有限公司 | 2022-11-15 | — | — | CN | disclosed |
| CN-211005191-U | Drug intermediate production device combination | 无棣融川医药化工科技有限公司 | 2020-07-14 | — | — | CN | disclosed |
| CN-107382892-A | A kind of preparation technology of the nitro isoxazole compound of 3 aryl 4 | 贵州大学 | 2017-11-24 | — | — | CN | disclosed |
| EP-2270894-A1 | Use of organic mesomeric compounds as dotands | Novaled AG (DE) | 2011-01-05 | — | — | EP | disclosed |
| EP-2083458-A1 | Organic mesomeric compounds as dotands | Novaled AG (DE) | 2009-07-29 | — | — | EP | disclosed |
| EP-1373247-A2 | SPIROISOQUINOLINE COMPOUNDS, METHODS FOR THEIR PREPARATION AND INTERMEDIATES THEREOF | TANABE SEIYAKU CO., LTD. (JP) | 2004-01-02 | — | — | EP | disclosed |
| CN-1129431-C | Combination of benzocycloheptapyridine compounds and antineoplastic drugs for treating proliferative diseases | SCHERING CORP (US) | 2003-12-03 | — | — | CN | disclosed |
| WO-1998011091-A2 | TRICYCLIC COMPOUNDS USEFUL FOR INHIBITION OF FARNESYL PROTEIN TRANSFERASE | SCHERING CORPORATION (US) | 1998-03-19 | — | — | WO | disclosed |
| CN-1036649-C | Alpha-unsaturated amines, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-12-10 | — | — | CN | disclosed |
| CN-1027447-C | Insecticidal/acaricidal composition containing alpha-unsaturated amine | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-01-18 | — | — | CN | disclosed |
| CN-1093083-A | The method for preparing α-unsaturated amine or its salt | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1994-10-05 | — | — | CN | disclosed |
| CN-1091737-A | The method for preparing amine compound or its salt | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1994-09-07 | — | — | CN | disclosed |
| CN-1055356-A | NITROENAMINE DERIVATIVES | CIBA GEIGY AG (CH) | 1991-10-16 | — | — | CN | disclosed |
| CN-1031079-A | Alpha-unsaturated amines, process for their production and their use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1989-02-15 | — | — | CN | disclosed |