Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 19/20 | 0.50 |
| ▸ | CTSK | P43235 | 17/20 | 0.50 |
| ▸ | CTSL | P07711 | 2/20 | 0.47 |
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7855743 | 0.85 | CTSS (0.55) | CTSSCTSKCTSLCTSB | |
| SCHEMBL29254677 | 0.85 | CTSS (0.51) | CTSSCTSKCTSLCTSB | |
| SCHEMBL29254679 | 0.85 | CTSS (0.51) | CTSSCTSKCTSLCTSB | |
| SCHEMBL6648220 | 0.83 | CTSK (0.46) | CTSSCTSKCTSLCTSB | |
| SCHEMBL6684772 | 0.82 | CA1 (0.49) | CTSSCTSKCTSLCTSB | |
| SCHEMBL18428079 | 0.81 | CA1 (0.42) | CTSSCTSKCTSLCTSB | |
| SCHEMBL4936593 | 0.81 | CTSK (0.51) | CTSSCTSK | |
| SCHEMBL30422267 | 0.81 | CA1 (0.42) | CTSSCTSKCTSLCTSB | |
| SCHEMBL29265449 | 0.81 | CA1 (0.42) | CTSSCTSKCTSLCTSB | |
| SCHEMBL1853923 | 0.81 | CTSK (0.51) | CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1117652-B1 | TAN-1057 DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2004-05-26 | — | — | EP | disclosed |
| US-6617332-B1 | Cyclic amidinourea derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2003-09-09 | — | — | US | disclosed |
| EP-1117652-A1 | TAN-1057 DERIVATIVES | Bayer Aktiengesellschaft (DE) | 2001-07-25 | — | — | EP | disclosed |
| WO-2000012484-A1 | TAN-1057 DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-03-09 | — | — | WO | disclosed |