Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 9/20 | 0.80 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.80 |
| ▸ | HTR2B | P41595 | 1/20 | 0.80 |
| ▸ | HIF1A | Q16665 | 9/20 | 0.68 |
| ▸ | AR | P10275 | 8/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.68 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.68 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diflucortolone Pivalate SCHEMBL668257 | 0.91 | PGR (0.81) | PGRNR1I2HTR2BHIF1AAR | |
| Diflucortolone Pivalate SCHEMBL668256 | 0.91 | PGR (0.81) | PGRNR1I2HTR2BHIF1AAR | |
| SCHEMBL11327698 | 0.90 | PGR (0.66) | PGRNR1I2HTR2BHIF1AAR | |
| SCHEMBL11121565 | 0.90 | PGR (0.66) | PGRNR1I2HTR2BHIF1AAR | |
| SCHEMBL11327696 | 0.90 | PGR (0.66) | PGRNR1I2HTR2BHIF1AAR | |
| Clocortolone Acetate SCHEMBL618722 | 0.90 | PGR (0.84) | PGRNR1I2HTR2BHIF1AAR | |
| Diflucortolone SCHEMBL10052991 | 0.89 | PGR (1.00) | PGRNR1I2HTR2BHIF1AAR | |
| Diflucortolone SCHEMBL22039899 | 0.89 | PGR (1.00) | PGRNR1I2HTR2BHIF1AAR | |
| Diflucortolone SCHEMBL22040571 | 0.89 | PGR (1.00) | PGRNR1I2HTR2BHIF1AAR | |
| Diflucortolone SCHEMBL3795 | 0.89 | PGR (1.00) | PGRNR1I2HTR2BHIF1AAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108472513-B | Hair growth compositions and methods | 强生消费者公司 | 2022-09-06 | — | — | CN | disclosed |
| CN-114222561-A | Alkaline phosphatase formulations and uses thereof | 合成生物制品有限公司 | 2022-03-22 | — | — | CN | disclosed |
| CN-101470103-B | Sterides compound analysis method | TIANJIN JINYAO GROUP Co.,Ltd. (CN) | 2011-12-14 | — | — | CN | disclosed |
| CN-101470103-A | Sterides compound analysis method | TIANJIN JINYAO GROUP CO LTD (CN) | 2009-07-01 | — | — | CN | disclosed |
| EP-1374861-A1 | External preparations for treating dermatoses | SEKISUI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2004-01-02 | — | — | EP | disclosed |
| EP-0766960-B1 | EXTERNAL PREPARATIONS FOR TREATING DERMATOSES | SEIKISUI CHEMICAL CO LTD (JP) | 2003-09-17 | — | — | EP | disclosed |
| US-6306898-B1 | MIXTURE OF VITAMIN E AND SQUALANE FOR SKIN DISORDERS | SEKISUI KAISHA KOGYO KABUSHIKI KAISHA (JP) | 2001-10-23 | — | — | US | disclosed |
| US-6248779-B1 | SYNERGISTIC MIXTURE OF VITAMIN E AND SQUALANE | SEKISUI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2001-06-19 | — | — | US | disclosed |
| EP-0766960-A1 | EXTERNAL PREPARATIONS FOR TREATING DERMATOSES | SEKISUI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1997-04-09 | — | — | EP | disclosed |