Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.31 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.31 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6650653 | 0.86 | ALDH1A1 (0.58) | ALDH1A1RAB9AHTTSMN1; SMN2POLB | |
| SCHEMBL6651785 | 0.84 | ALDH1A1 (0.57) | ALDH1A1RAB9AHTTSMN1; SMN2POLB | |
| SCHEMBL27913397 | 0.84 | NOTUM (0.47) | ALDH1A1NOTUMSMPD1TMPRSS15 | |
| SCHEMBL16571266 | 0.82 | ALDH1A1 (0.48) | ALDH1A1RAB9ASMN1; SMN2POLBNPC1 | |
| SCHEMBL29438935 | 0.82 | NOTUM (0.46) | ALDH1A1NOTUMSMPD1TMPRSS15 | |
| SCHEMBL10417226 | 0.80 | ALDH1A1 (0.57) | ALDH1A1RAB9ASMN1; SMN2LMNANPC1 | |
| SCHEMBL6651488 | 0.79 | ALDH1A1 (0.59) | ALDH1A1RAB9AHTTSMN1; SMN2LMNA | |
| SCHEMBL5987816 | 0.73 | ALDH1A1 (0.44) | ALDH1A1RAB9AHTTSMN1; SMN2POLB | |
| SCHEMBL3765497 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL6822779 | 0.72 | ALDH1A1 (0.43) | ALDH1A1RAB9AHTTSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0956294-B1 | THROMBIN INHIBITORS | ABBOTT GMBH & CO KG (DE) | 2004-06-09 | — | — | EP | disclosed |
| EP-1165601-A2 | PRODRUGS OF THROMBIN INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 2002-01-02 | — | — | EP | disclosed |
| EP-1051431-A1 | THROMBIN INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 2000-11-15 | — | — | EP | disclosed |
| WO-2000061609-A2 | PRODRUGS OF THROMBIN INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 2000-10-19 | — | — | WO | disclosed |
| EP-0956294-A1 | THROMBIN INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1999-11-17 | — | — | EP | disclosed |
| WO-1999037668-A1 | THROMBIN INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1999-07-29 | — | — | WO | disclosed |
| WO-1998006741-A1 | THROMBIN INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1998-02-19 | — | — | WO | disclosed |