Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.51 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | BCL2 | P10415 | 1/20 | 0.46 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | DRD5 | P21918 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2208190 | 0.98 | DRD2 (0.52) | DRD2DRD4PDE3BPDE3AHRH3 | |
| Hydrochloric Acid SCHEMBL2208192 | 0.98 | DRD2 (0.52) | DRD2DRD4PDE3BPDE3AHRH3 | |
| SCHEMBL665048 | 0.89 | CA12 (0.53) | DRD2DRD4PDE3BPDE3AHRH3 | |
| Hydrochloric Acid SCHEMBL8021718 | 0.87 | KDM4E (0.53) | DRD2DRD4PDE3BPDE3AHRH3 | |
| SCHEMBL2778234 | 0.87 | HRH3 (0.48) | DRD2DRD4PDE3BPDE3AHRH3 | |
| Hydrochloric Acid SCHEMBL3526192 | 0.86 | KDM4E (0.48) | DRD2DRD4PDE3BPDE3AHRH3 | |
| SCHEMBL30025932 | 0.85 | HTR2C (0.50) | DRD2PDE3BPDE3AHRH3HTR2C | |
| SCHEMBL550150 | 0.85 | HTR2C (0.50) | DRD2PDE3BPDE3AHRH3HTR2C | |
| SCHEMBL20956992 | 0.82 | TNIK (0.56) | DRD2DRD4HTR2CHTR2BTNIK | |
| SCHEMBL12079387 | 0.82 | PDE3B (0.61) | PDE3BPDE3AHTR2CBCL2TNIK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 240 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117229275-B | Novel 2-acetamido thiazole compound and preparation method and application thereof | 北京中医药大学 | 2024-06-18 | — | — | CN | claimed |
| CN-115626889-B | Organic chemical conversion method for oxidative dehydrogenation of nitrogen-containing heterocyclic compound | 南京工业大学 | 2024-04-30 | — | — | CN | claimed |
| CN-115353478-A | Preparation method of indole compound | 南京工业大学 | 2022-11-18 | — | — | CN | claimed |
| CN-115160824-A | Method for preparing multicolor dye from single polymer | 四川大学 | 2022-10-11 | — | — | CN | claimed |
| US-20190127345-A1 | NEGATIVE PHOTOCHROMIC MATERIALS WITH TUNABLE PROPERTIES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-05-02 | — | — | US | claimed |
| WO-2017189700-A1 | NEGATIVE PHOTOCHROMIC MATERIALS WITH TUNABLE PROPERTIES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-11-02 | — | — | WO | claimed |
| JP-9278752-A | — | — | None | — | — | JP | disclosed |
| EP-4142732-B1 | METHODS OF USE FOR PYRIMIDINES AS FERROPORTIN INHIBITORS | GLOBAL BLOOD THERAPEUTICS INC (US) | 2026-04-22 | — | — | EP | disclosed |
| US-12599584-B2 | Indoline derivatives, compositions comprising them and uses thereof | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2026-04-14 | — | — | US | disclosed |
| EP-4692071-A1 | PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASS | TOKUYAMA CORPORATION (JP) | 2026-02-11 | — | — | EP | disclosed |
| US-20250122152-A1 | KAT6 Inhibitors | BEIGENE SWITZERLAND GMBH (CH) | 2025-04-17 | — | — | US | disclosed |
| US-20250109122-A1 | CYCLOALKYL PYRIMIDINES AS FERROPORTIN INHIBITORS | GLOBAL BLOOD THERAPEUTICS INC (US) | 2025-04-03 | — | — | US | disclosed |
| WO-2025068943-A1 | KAT6 INHIBITORS | BEIGENE SWITZERLAND GMBH (CH) | 2025-04-03 | — | — | WO | disclosed |
| EP-0159376-A1 | 1-(Aminoalkylphenyl and Aminoalkylbenzyl)-indoles and indolines, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1985-10-30 | — | — | EP | disclosed |
| US-4532333-A | ANALGESICS | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1985-07-30 | — | — | US | disclosed |
| US-4448784-A | 1-(Aminoalkylphenyl and aminoalkylbenzyl)-indoles and indolines and analgesic method of use thereof | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1984-05-15 | — | — | US | disclosed |
| US-4377699-A | REACTING INDOLINE WITH AN ORGANIC CARBOXYLIC ACID ACYLATING AGENT, CHLORINATION, SAPONIFICATION, FOLLOWED BY OXIDATION WITH AN AROMATIC NITRO COMPOUND | RUTGERSWERKE AKTIENGESELLSCHAFT (DE) | 1983-03-22 | — | — | US | disclosed |
| EP-0004494-B1 | DERIVATIVES OF 1,3-DIHYDRO-3-(1-(2-(2,3-DIHYDRO-1,4-BENZODIOXIN-2-YL)2-HYDROXYETHYL)PIPERIDIN-4-YL)2H-INDOL-2-ON, PROCESS FOR THEIR PREPARATION, THEIR USE AS MEDICAMENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1982-02-17 | — | — | EP | disclosed |
| EP-0004494-A1 | Derivatives of 1,3-dihydro-3-(1-(2-(2,3-dihydro-1,4-benzodioxin-2-yl)2-hydroxyethyl)piperidin-4-yl)2H-indol-2-on, process for their preparation, their use as medicaments and pharmaceutical compositions containing them | ROUSSEL-UCLAF (FR) | 1979-10-03 | — | — | EP | disclosed |
| US-4017484-A | Cationic dyestuffs | BAYER AKTIENGESELLSCHAFT (DT) | 1977-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250122152-A1 | KAT6 Inhibitors | KAT6A, KAT6B, KAT7 | DRD2 4083/4885DRD4 3715/4885PDE3B 3902/4885 |
| US-20190127345-A1 | NEGATIVE PHOTOCHROMIC MATERIALS WITH TUNABLE PROPERTIES | ALKBH2, YTHDF2, ANXA2 | DRD2 302/4885DRD4 155/4885PDE3B 2944/4885 |
| US-20250109122-A1 | CYCLOALKYL PYRIMIDINES AS FERROPORTIN INHIBITORS | HAMP, SLC40A1, FANCI | DRD2 3430/4885DRD4 3932/4885PDE3B 2809/4885 |
| US-12599584-B2 | Indoline derivatives, compositions comprising them and uses thereof | IL6, TNF, IDO1 | DRD2 1142/4885DRD4 1750/4885PDE3B 840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.