Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.33 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6650904 | 0.77 | HTR3A (0.36) | HRH4HTR3ADPP4KDM1A | |
| SCHEMBL6319564 | 0.74 | ALDH1A1 (0.47) | SMN1; SMN2NPSR1 | |
| SCHEMBL6320019 | 0.66 | HRH4 (0.34) | HRH4HTR3ADPP4KDM1A | |
| SCHEMBL604702 | 0.61 | HRH4 (0.59) | HRH4DPP4 | |
| SCHEMBL17198089 | 0.61 | BPTF (0.51) | HRH4HTR3ACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL602330 | 0.60 | HRH4 (0.56) | HRH4HTR3ADPP4 | |
| Hydrochloric Acid SCHEMBL602958 | 0.60 | HRH4 (0.58) | HRH4DPP4 | |
| SCHEMBL602797 | 0.60 | HRH4 (0.67) | HRH4HTR3A | |
| Hydrochloric Acid SCHEMBL605480 | 0.60 | HRH4 (0.56) | HRH4HTR3ADPP4 | |
| Hydrochloric Acid SCHEMBL6532118 | 0.60 | HRH4 (0.44) | HRH4HTR3ADPP4KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1479681-A1 | IMIDAZO(1,2-a)PYRIDINE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-11-24 | — | — | EP | disclosed |