Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 11/20 | 0.71 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | HTR1D | P28221 | 3/20 | 0.55 |
| ▸ | OGG1 | O15527 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.53 |
| ▸ | HRH1 | P35367 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30825865 | 0.83 | HTR1B (1.00) | HTR1BNR2E1KDM4EKCNA3ALDH1A1 | |
| SCHEMBL9523932 | 0.83 | HTR1B (1.00) | HTR1BNR2E1KDM4EKCNA3ALDH1A1 | |
| SCHEMBL15295198 | 0.83 | HTR1B (0.71) | HTR1BNR2E1KDM4EKCNA3ALDH1A1 | |
| SCHEMBL5289923 | 0.82 | HTR1B (0.77) | HTR1BNR2E1KDM4EKCNA3ALDH1A1 | |
| SCHEMBL16902842 | 0.82 | HTR1B (0.64) | HTR1BNR2E1KDM4EKCNA3ALDH1A1 | |
| SCHEMBL7206887 | 0.82 | HTR1B (1.00) | HTR1BNR2E1KCNA3TDP1HTR1D | |
| Hydrochloric Acid SCHEMBL27274284 | 0.80 | HTR1B (0.96) | HTR1BNR2E1KDM4EKCNA3TDP1 | |
| SCHEMBL10527536 | 0.80 | HTR1B (0.89) | HTR1BNR2E1KCNA3TDP1HTR1D | |
| SCHEMBL9770352 | 0.80 | KCNA3 (0.81) | HTR1BNR2E1KCNA3TDP1HTR1D | |
| SCHEMBL2177350 | 0.80 | HTR1B (0.78) | HTR1BNR2E1KCNA3TDP1HTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1425261-A2 | METHOD FOR PRODUCING 4-AMINO-1-NAPHTHOL ETHERS | Bayer Chemicals AG (DE) | 2004-06-09 | — | — | EP | disclosed |
| WO-2003020686-A2 | METHOD FOR PRODUCING 4-AMINO-1-NAPHTHOL ETHERS | BAYER CHEMICALS AG (DE) | 2003-03-13 | — | — | WO | disclosed |
| EP-0148201-A4 | NAPHTALENE AMINOALKYLENE ETHERS AND THIOETHERS, AND THEIR PHARMA CEUTICAL USES. | RORER INTERNAT OVERSEAS INC (US) | 1985-09-26 | — | — | EP | disclosed |
| US-4543352-A | ANTISECRETORY, ANTIULCER, ANTACID, HISTAMINE H2-ANTAGONISTS | WILLIAM H. RORER, INC. (US) | 1985-09-24 | — | — | US | disclosed |
| EP-0148201-A1 | NAPHTALENE AMINOALKYLENE ETHERS AND THIOETHERS, AND THEIR PHARMA CEUTICAL USES | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1985-07-17 | — | — | EP | disclosed |
| WO-1984004245-A1 | NAPHTALENE AMINOALKYLENE ETHERS AND THIOETHERS, AND THEIR PHARMA CEUTICAL USES | RORER INT OVERSEAS (US) | 1984-11-08 | — | — | WO | disclosed |