Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 8/20 | 0.34 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | PKM | P14618 | 4/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | PKLR | P30613 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | TOP2A | P11388 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6651342 | 0.84 | CREBBP (0.44) | CREBBPGAAMAPTPKMTP53 | |
| SCHEMBL5168296 | 0.82 | PKM (0.45) | GAAMAPTPKMTP53SMN1; SMN2 | |
| SCHEMBL6650594 | 0.77 | CREBBP (0.41) | CREBBPGAAMAPTPKMTP53 | |
| SCHEMBL5165682 | 0.76 | CREBBP (0.35) | CREBBPKMT2A | |
| SCHEMBL6652419 | 0.74 | GAA (0.51) | CREBBPGAAMAPTPKMTP53 | |
| SCHEMBL5168437 | 0.74 | GAA (0.43) | CREBBPGAAMAPTPKMTP53 | |
| Hydrochloric Acid SCHEMBL6649161 | 0.74 | GAA (0.50) | CREBBPGAAMAPTPKMTP53 | |
| SCHEMBL6651479 | 0.73 | CREBBP (0.57) | CREBBPGAAMAPTPKMTP53 | |
| SCHEMBL5167429 | 0.69 | CREBBP (0.58) | CREBBPGAAMAPTPKMTP53 | |
| SCHEMBL6654641 | 0.68 | CREBBP (0.49) | CREBBPGAAMAPTPKMTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218378-B1 | TERT.-BUTYL-(7-METHYL-IMIDAZO[1,2-A]PYRIDINE-3-YL)-AMINE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2003-04-23 | — | — | EP | claimed |
| EP-1326613-B1 | USE OF SUBSTITUTED IMIDAZO 1,2-A]PYRIDINE-, IMIDAZO [1,2-A]PYRIMIDINE AND IMIDAZO [1,2-A]PYRAZINE-3-YL-AMINE DERIVATIVES FOR PRODUCING NOS-INHIBITING MEDICAMENTS | GRUENENTHAL GMBH (DE) | 2004-06-02 | — | — | EP | disclosed |
| EP-1218378-B1 | TERT.-BUTYL-(7-METHYL-IMIDAZO[1,2-A]PYRIDINE-3-YL)-AMINE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2003-04-23 | — | — | EP | disclosed |