Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.44 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5891678 | 0.94 | AVPR2 (0.48) | AVPR2LMNAPOLBTP53ROCK2 | |
| SCHEMBL5891358 | 0.93 | AVPR2 (0.49) | AVPR2LMNAPOLBTP53ROCK2 | |
| SCHEMBL5891149 | 0.91 | AVPR2 (0.46) | AVPR2LMNAPOLBTP53ROCK2 | |
| SCHEMBL5890729 | 0.91 | AVPR2 (0.50) | AVPR2LMNAPOLBTP53AVPR1A | |
| SCHEMBL5890574 | 0.90 | AVPR2 (0.46) | AVPR2LMNAPOLBTP53ROCK2 | |
| SCHEMBL5890848 | 0.88 | AVPR2 (0.46) | AVPR2LMNAPOLBTP53ROCK2 | |
| SCHEMBL5890810 | 0.86 | ROCK2 (0.42) | AVPR2LMNAROCK2ROCK1 | |
| SCHEMBL3537560 | 0.86 | AVPR2 (0.50) | AVPR2LMNATP53ROCK2ROCK1 | |
| SCHEMBL5891677 | 0.86 | ROCK2 (0.48) | AVPR2POLBROCK2ROCK1MEN1 | |
| SCHEMBL5891209 | 0.85 | ALDH1A1 (0.48) | AVPR2POLBTP53ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002083683-A9 | NOVEL TRICYCLIC PYRIDYL BENZAZEPINE CARBOXAMIDES AND DERIVATIVES THEREOF TOCOLYTIC OXYTOCIN RECEPTOR ANTAGONISTS | WYETH CORP (US) | 2004-02-26 | — | — | WO | disclosed |