Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | TARBP2 | Q15633 | 2/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | PDCD4 | Q53EL6 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28455199 | 0.88 | ALDH1A1 (0.56) | MAPTALDH1A1IDO1GAAKDM4E | |
| SCHEMBL10439147 | 0.85 | SMN1; SMN2 (0.59) | ALDH1A1GAAKDM4ESMN1; SMN2POLB | |
| SCHEMBL6618657 | 0.83 | KDM4E (0.50) | MAPTALDH1A1GAAKDM4EHSD17B10 | |
| SCHEMBL6497228 | 0.77 | ALDH1A1 (0.55) | NPC1MAPTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8234965 | 0.76 | ATM (0.54) | NPC1PKMMAPTALDH1A1GAA | |
| SCHEMBL2823777 | 0.75 | MAPK1 (0.51) | ALDH1A1GAAKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL9877360 | 0.74 | SMN1; SMN2 (0.65) | NPC1MAPTALDH1A1GAAKDM4E | |
| SCHEMBL7206290 | 0.74 | MAPK1 (0.49) | ALDH1A1GAAKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL10439316 | 0.74 | ALDH1A1 (0.48) | NPC1PKMMAPTALDH1A1GAA | |
| SCHEMBL4492226 | 0.73 | ALDH1A1 (0.54) | NPC1PKMALDH1A1GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1485379-A1 | BETA 3-ADRENERGIC RECEPTOR AGONISTS | Pfizer Products Inc. (US) | 2004-12-15 | — | — | EP | disclosed |
| WO-2003072572-A1 | BETA3-ADRENERGIC RECEPTOR AGONISTS | PFIZER PRODUCTS INC. (US) | 2003-09-04 | — | — | WO | disclosed |