Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 7/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 6/20 | 0.48 |
| ▸ | SLC1A2 | P43004 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | METAP1 | P53582 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6652464 | 1.00 | SLC1A1 (0.48) | SLC1A1SLC1A3SLC1A2MEN1KMT2A | |
| SCHEMBL9265345 | 0.80 | SLC1A3 (0.45) | SLC1A1SLC1A3SLC1A2MEN1KMT2A | |
| SCHEMBL4451525 | 0.79 | EPHX2 (0.46) | SLC1A1SLC1A3SLC1A2MEN1KMT2A | |
| SCHEMBL6473457 | 0.76 | IDO1 (0.53) | KMT2ACYP2C9CYP2C19METAP2METAP1 | |
| SCHEMBL9450992 | 0.76 | SLC1A1 (0.54) | SLC1A1SLC1A3SLC1A2MEN1KMT2A | |
| SCHEMBL8759874 | 0.75 | METAP2 (0.47) | MEN1KMT2ACYP2C9CYP2C19METAP2 | |
| Hydrochloric Acid SCHEMBL3823025 | 0.75 | IDO1 (0.52) | KMT2ACYP2C9CYP2C19METAP2METAP1 | |
| SCHEMBL6479809 | 0.75 | IDO1 (0.52) | MEN1KMT2ACYP2C9CYP2C19METAP2 | |
| Hydrochloric Acid SCHEMBL9516057 | 0.74 | METAP2 (0.49) | SLC1A1SLC1A3SLC1A2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9516061 | 0.74 | METAP2 (0.49) | SLC1A1SLC1A3SLC1A2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000061134-A9 | ANTIMICROBIAL AGENTS | BRITISH BIOTECH PHARM (GB) | 2004-04-22 | — | — | WO | disclosed |
| US-6716878-B1 | BACTERICIDE, ANTIPROTOZOAL; VANCOMYCIN RESISTANT ENTEROCOCCI AND BETA-LACTAM ANTIBIOTIC-RESISTANT BACTERIA, METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; HYDROXAMIC ACID AND N-FORMYL SUBTITUTED ALKYLAMIDES | VERNALIS (OXFORD) LIMITED (GB) | 2004-04-06 | — | — | US | disclosed |
| EP-1169031-A1 | ANTIMICROBIAL AGENTS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2002-01-09 | — | — | EP | disclosed |
| WO-2000061134-A1 | ANTIMICROBIAL AGENTS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2000-10-19 | — | — | WO | disclosed |