Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | METAP2 | P50579 | 1/20 | 0.47 |
| ▸ | METAP1 | P53582 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3823025 | 0.99 | IDO1 (0.52) | IDO1CYP2C19CYP3A4CYP2C9METAP2 | |
| SCHEMBL6479809 | 0.99 | IDO1 (0.52) | IDO1CYP2C19CYP3A4CYP2C9METAP2 | |
| Hydrochloric Acid SCHEMBL7297833 | 0.97 | IDO1 (0.51) | IDO1CYP2C19CYP3A4CYP2C9METAP2 | |
| Hydrochloric Acid SCHEMBL3825774 | 0.97 | IDO1 (0.51) | IDO1CYP2C19CYP3A4CYP2C9METAP2 | |
| SCHEMBL25597938 | 0.94 | IDO1 (0.55) | IDO1CYP2C19CYP3A4CYP2C9SLC6A2 | |
| SCHEMBL27504573 | 0.94 | IDO1 (0.55) | IDO1CYP2C19CYP3A4CYP2C9SLC6A2 | |
| SCHEMBL14190212 | 0.94 | IDO1 (0.55) | IDO1CYP2C19CYP3A4CYP2C9SLC6A2 | |
| Hydrochloric Acid SCHEMBL3820370 | 0.93 | IDO1 (0.54) | IDO1CYP2C19CYP3A4CYP2C9SLC6A2 | |
| Trifluoroacetic Acid SCHEMBL7206393 | 0.91 | IDO1 (0.46) | IDO1CYP2C19CYP3A4CYP2C9METAP2 | |
| SCHEMBL30695257 | 0.86 | ALDH1A1 (0.46) | CYP2C19CYP3A4CYP2C9METAP2METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050075281-A1 | peptide antibiotics comprising lysobactin derivatives used for treatment and/or prophylaxis of bacterial infectious diseases; cyclic peptides | BAYER HEALTHCARE AG (DE) | 2005-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075281-A1 | peptide antibiotics comprising lysobactin derivatives used for treatment and/or prophylaxis of bacterial infectious diseases; cyclic peptides | VIP, LNPEP, HAMP | IDO1 2451/4885CYP2C19 2626/4885CYP3A4 4606/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.