Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SCN4A | P35499 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | LSS | P48449 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17991058 | 0.80 | KDM1A (0.60) | LMNAMAOAKDM1AMAOBPKM | |
| SCHEMBL27548952 | 0.79 | LMNA (0.50) | LMNASCN4AMAOAMAPTPTGS1 | |
| SCHEMBL14546274 | 0.78 | LMNA (0.59) | LMNAMAOAKDM1AMAOBPKM | |
| SCHEMBL14672093 | 0.78 | MAPT (0.57) | LMNAMAOAKDM1AMAOBLSS | |
| SCHEMBL7101433 | 0.78 | LMNA (0.48) | LMNASCN4AMAOAPTGS1ALDH1A1 | |
| SCHEMBL17425093 | 0.78 | LMNA (0.53) | LMNASCN4AMAOAPTGS1CHRNA7 | |
| SCHEMBL15672914 | 0.76 | KCNA3 (0.64) | LSSPKMCHRNA7ALDH1A1LTA4H | |
| SCHEMBL15383159 | 0.76 | LSS (0.52) | LMNALSSMAPTCHRNA7ALDH1A1 | |
| SCHEMBL9229780 | 0.76 | LMNA (0.56) | LMNASCN4AMAOAPTGS1ALDH1A1 | |
| SCHEMBL14954600 | 0.76 | LMNA (0.56) | LMNASCN4AMAOAPTGS1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1380562-A1 | CARBOXYLIC ACID DERIVATIVE AND SALT THEREOF | Eisai Co., Ltd. (JP) | 2004-01-14 | — | — | EP | disclosed |