Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SCN4A | P35499 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27864161 | 0.82 | LMNA (0.47) | LMNASCN4AMAOAPTGS1KCNA3 | |
| SCHEMBL27548952 | 0.81 | LMNA (0.50) | LMNASCN4AMAOAPTGS1KCNA3 | |
| SCHEMBL17425093 | 0.79 | LMNA (0.53) | LMNASCN4AMAOAPTGS1KCNA3 | |
| SCHEMBL28527689 | 0.78 | LMNA (0.52) | LMNASCN4AMAOAPTGS1KCNA3 | |
| SCHEMBL14954600 | 0.78 | LMNA (0.56) | LMNASCN4AMAOAPTGS1KCNA3 | |
| SCHEMBL9229780 | 0.78 | LMNA (0.56) | LMNASCN4AMAOAPTGS1KCNA3 | |
| SCHEMBL6651790 | 0.78 | LMNA (0.47) | LMNASCN4AMAOAPTGS1KCNA3 | |
| SCHEMBL9816273 | 0.77 | LMNA (0.50) | LMNASCN4AMAOAPTGS1KCNA3 | |
| SCHEMBL3824504 | 0.76 | LMNA (0.46) | LMNASCN4AMAOAPTGS1KCNA3 | |
| SCHEMBL28025665 | 0.76 | LMNA (0.50) | LMNASCN4AMAOAPTGS1KCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003095441-A1 | INHIBITORS OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME | PFIZER INC. (US) | 2003-11-20 | — | — | WO | disclosed |