SCHEMBL665188

SCHEMBL665188

CCCCC1(CCCC)c2ccccc2-c2ccc(N(c3ccc4c(c3)C(CCCC)(CCCC)c3ccccc3-4)c3ccc4c(c3)C(CCCC)(CCCC)c3cc(Br)ccc3-4)cc21

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 9/20 0.39
APEX1 P27695 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
OPRM1 P35372 1/20 0.31
OPRD1 P41143 1/20 0.31
CYP1A2 P05177 1/20 0.30
MAPK1 P28482 1/20 0.30
ELANE P08246 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15399801 0.94 MEN1 (0.36) PDK2MEN1KMT2AOPRM1CYP1A2
SCHEMBL12900224 0.91 PDK2 (0.36) PDK2APEX1MEN1KMT2ACYP1A2
SCHEMBL23320304 0.91 PDK2 (0.36) PDK2APEX1MEN1KMT2ACYP1A2
SCHEMBL30185539 0.91 PDK2 (0.45) PDK2APEX1MEN1KMT2AOPRM1
SCHEMBL1547059 0.91 PDK2 (0.45) PDK2APEX1MEN1KMT2AOPRM1
SCHEMBL27937227 0.90 MEN1 (0.35) PDK2MEN1KMT2AELANE
SCHEMBL13931287 0.89 PDK2 (0.40) PDK2APEX1OPRM1CYP1A2ELANE
SCHEMBL27746236 0.89 PDK2 (0.40) PDK2APEX1OPRM1CYP1A2ELANE
SCHEMBL16556475 0.89 MEN1 (0.33) PDK2MEN1KMT2AELANE
SCHEMBL2601870 0.89 MMP2 (0.36) PDK2MEN1KMT2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8419808-B2 Dye compound and photoelectric component using the same EVERLIGHT USA, INC. (US) 2013-04-16 US disclosed
US-8419808-B2 Dye compound and photoelectric component using the same EVERLIGHT USA, INC. (US) 2013-04-16 US disclosed
US-8419808-B2 Dye compound and photoelectric component using the same EVERLIGHT USA, INC. (US) 2013-04-16 US disclosed
US-8203068-B2 Dye compound and photoelectric component using the same EVERLIGHT USA, INC. (US) 2012-06-19 US disclosed
US-8203068-B2 Dye compound and photoelectric component using the same EVERLIGHT USA, INC. (US) 2012-06-19 US disclosed
US-8203068-B2 Dye compound and photoelectric component using the same EVERLIGHT USA, INC. (US) 2012-06-19 US disclosed
US-20120042457-A1 DYE COMPOUND AND PHOTOELECTRIC COMPONENT USING THE SAME EVERLIGHT USA, INC. (US) 2012-02-23 US disclosed
US-20120042457-A1 DYE COMPOUND AND PHOTOELECTRIC COMPONENT USING THE SAME EVERLIGHT USA, INC. (US) 2012-02-23 US disclosed
CN-101735639-A Dye compound and photoelectric assembly manufactured by same MINGDE INTERNAT WAREHOUSING AN 2010-06-16 CN disclosed
US-20100122729-A1 Dye compound and photoelectric component using the same EVERLIGHT USA, INC. (US) 2010-05-20 US disclosed
US-20100122729-A1 Dye compound and photoelectric component using the same EVERLIGHT USA, INC. (US) 2010-05-20 US disclosed
US-20100122729-A1 Dye compound and photoelectric component using the same EVERLIGHT USA, INC. (US) 2010-05-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120042457-A1 DYE COMPOUND AND PHOTOELECTRIC COMPONENT USING THE SAME CRY1, SCNN1B, SMARCC2 PDK2 1668/4885APEX1 2783/4885MEN1 1275/4885
US-20100122729-A1 Dye compound and photoelectric component using the same CRY1, SCNN1B, SMARCC2 PDK2 1668/4885APEX1 2783/4885MEN1 1275/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.