Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 6/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | NDUFS8 | O00217 | 1/20 | 0.56 |
| ▸ | COXFA4 | O00483 | 1/20 | 0.56 |
| ▸ | NDUFAB1 | O14561 | 1/20 | 0.56 |
| ▸ | NDUFA1 | O15239 | 1/20 | 0.56 |
| ▸ | NDUFS4 | O43181 | 1/20 | 0.56 |
| ▸ | NDUFB5 | O43674 | 1/20 | 0.56 |
| ▸ | NDUFB3 | O43676 | 1/20 | 0.56 |
| ▸ | NDUFC1 | O43677 | 1/20 | 0.56 |
| ▸ | NDUFA2 | O43678 | 1/20 | 0.56 |
| ▸ | NDUFS5 | O43920 | 1/20 | 0.56 |
| ▸ | NDUFS7 | O75251 | 1/20 | 0.56 |
| ▸ | NDUFS2 | O75306 | 1/20 | 0.56 |
| ▸ | NDUFS6 | O75380 | 1/20 | 0.56 |
| ▸ | NDUFB1 | O75438 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6652010 | 1.00 | ALOX15 (0.56) | ALOX15TDP1MTNR1AMAPTHPGD | |
| SCHEMBL9058093 | 0.94 | MTNR1A (0.55) | ALOX15TDP1MTNR1AMAPTHPGD | |
| SCHEMBL9058090 | 0.94 | MTNR1A (0.55) | ALOX15TDP1MTNR1AMAPTHPGD | |
| SCHEMBL4653735 | 0.93 | KDM4E (0.56) | ALOX15TDP1MTNR1AMAPTHPGD | |
| SCHEMBL4653737 | 0.93 | KDM4E (0.56) | ALOX15TDP1MTNR1AMAPTHPGD | |
| SCHEMBL6656213 | 0.93 | MTNR1A (0.56) | ALOX15TDP1MTNR1AMAPTHPGD | |
| SCHEMBL6655312 | 0.93 | MTNR1A (0.56) | ALOX15TDP1MTNR1AMAPTHPGD | |
| SCHEMBL6651695 | 0.91 | ALOX15 (0.55) | ALOX15TDP1MTNR1AMAPTHPGD | |
| SCHEMBL6651692 | 0.91 | ALOX15 (0.55) | ALOX15TDP1MTNR1AMAPTHPGD | |
| SCHEMBL3302293 | 0.89 | MAOB (0.55) | ALOX15TDP1MTNR1AMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0875501-B1 | Alkylenediamine derivative, anti-ulcer drug, and antibacterial drug | SHISEIDO CO LTD (JP) | 2004-06-16 | — | — | EP | disclosed |
| EP-0802196-B1 | Alkylenediamine derivatives as drugs for the treatment of ulcers and the inhibition of Helicobacter pylori | SHISEIDO CO LTD (JP) | 2001-08-29 | — | — | EP | disclosed |
| US-6043243-A | Pyrrolidine derivative, anti-ulcer drug, and antibacterial drug | SHISEIDO CO., LTD. (JP) | 2000-03-28 | — | — | US | disclosed |
| US-6001880-A | DISUBSTITUTED N-(2-DIALKYLAMINOETHYL)BENZAMIDE DERIVATIVES OF GIVEN FORMULA; ANTIBACTERIAL ACTIVITY AGAINST HELICOBACTER PYROLI, ADMINISTERING FOR THE PREVENTION OR CURE OF PEPTIC ULCERS | SHISEIDO CO., LTD. (JP) | 1999-12-14 | — | — | US | disclosed |
| US-5925667-A | INHIBITS GROWTH OF HELICOBACTER PYLORI | SHISEIDO CO., LTD. (JP) | 1999-07-20 | — | — | US | disclosed |
| EP-0875501-A2 | Alkylenediamine derivative, anti-ulcer drug, and antibacterial drug | SHISEIDO COMPANY LIMITED (JP) | 1998-11-04 | — | — | EP | disclosed |
| EP-0869118-A1 | Pyrrolidine derivative, anti-ulcer drug, and antibacterial drug | SHISEIDO COMPANY LIMITED (JP) | 1998-10-07 | — | — | EP | disclosed |
| US-5814634-A | PEPTIC ULCERS, GASTRIC ULCERS | SHISEIDO CO. LTD. (JP) | 1998-09-29 | — | — | US | disclosed |
| EP-0802196-A1 | Alkylenediamine derivative, antiulcer drug, and antibacterial drug | SHISEIDO COMPANY LIMITED (JP) | 1997-10-22 | — | — | EP | disclosed |