SCHEMBL6652423

SCHEMBL6652423

O=[N+]([O-])c1ccc(S(=O)O)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 2/20 0.50
CA1 P00915 3/20 0.48
CA2 P00918 3/20 0.48
TDP1 Q9NUW8 1/20 0.48
ALDH1A1 P00352 3/20 0.48
ACHE P22303 1/20 0.48
HSD17B10 Q99714 1/20 0.48
TSHR P16473 2/20 0.47
MAPK1 P28482 1/20 0.47
LMNA P02545 1/20 0.46
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
CYP1A2 P05177 1/20 0.44
CYP2C19 P33261 1/20 0.44
MMP1 P03956 1/20 0.44
MMP2 P08253 1/20 0.44
MMP9 P14780 1/20 0.44
MMP8 P22894 1/20 0.44
MMP13 P45452 1/20 0.44
CES2 O00748 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11302917 0.98 CES1 (0.48) CES1CA1CA2TDP1ALDH1A1
SCHEMBL1584829 0.98 CES1 (0.48) CES1CA1CA2TDP1ALDH1A1
SCHEMBL6693542 0.98 CES1 (0.48) CES1CA1CA2TDP1ALDH1A1
SCHEMBL6690834 0.98 CES1 (0.48) CES1CA1CA2TDP1ALDH1A1
Silver SCHEMBL11302915 0.77 ALDH1A1 (0.48) CES1CA1CA2TDP1ALDH1A1
Potassium Ion SCHEMBL6693540 0.77 ALDH1A1 (0.48) CES1CA1CA2TDP1ALDH1A1
SCHEMBL1584828 0.77 ALDH1A1 (0.48) CES1CA1CA2TDP1ALDH1A1
Lithium Ion SCHEMBL6690832 0.77 ALDH1A1 (0.48) CES1CA1CA2TDP1ALDH1A1
Hydrogen Peroxide SCHEMBL28789390 0.77 ALDH1A1 (0.72) CES1CA1CA2TDP1ALDH1A1
SCHEMBL22567 0.77 ALDH1A1 (0.72) CES1CA1CA2TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116574038-B Preparation method of N-aryl sulfonamide derivative 安阳师范学院 2025-04-18 CN claimed
CN-116574038-A Preparation method of N-aryl sulfonamide derivative 安阳师范学院 2023-08-11 CN claimed
CN-109183392-A Graphene denatured conductive cellulose fibre and its preparation method and application 青岛大学 2019-01-11 CN claimed
CN-109183393-A Graphene denatured conductive protein fibre and its preparation method and application 青岛大学 2019-01-11 CN claimed
CN-109162088-A Graphene denatured conductive synthetic fibers and its preparation method and application 青岛大学 2019-01-08 CN claimed
CN-104628606-A Preparation method of sulfohydrazide compound WANG HUA 2015-05-20 CN claimed
CN-103641674-B Method for preparing diaryl sulfone ZHEJIANG ZHONGXIN CHEMICALS CO LTD 2015-04-08 CN claimed
CN-103172479-B Preparation method for biaryl through palladium catalysis SHAOXING UNIVERSITY (CN) 2014-10-29 CN claimed
CN-104072323-A Symmetric biphenyl preparation method UNIV SHAOXING 2014-10-01 CN claimed
CN-103922976-A Asymmetric diaryl sulfone compound and preparation method thereof UNIV SHAOXING 2014-07-16 CN claimed
CN-103641674-A Method for preparing diaryl sulfone ZHEJIANG ZHONGXIN CHEMICALS CO LTD 2014-03-19 CN claimed
CN-103172479-A Preparation method for biaryl through palladium catalysis UNIV SHAOXING 2013-06-26 CN claimed
US-4039334-A ORGANIC SILVER SALT AND HALIDE, REDUCING AGENT, ROSIN FUJI PHOTO FILM CO., LTD. (JA) 1977-08-02 US claimed
CN-122031506-A Chiral control 波涛生命科学有限公司 2026-05-15 CN disclosed
CN-116574038-B Preparation method of N-aryl sulfonamide derivative 安阳师范学院 2025-04-18 CN disclosed
CN-117623838-A Chiral sulfoxide ester compound and preparation method thereof 贵州大学 2024-03-01 CN disclosed
US-4740596-A Process for preparation of 4-sulfonylthio azetidinone derivatives OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 1988-04-26 US disclosed
EP-0249024-A1 Aromatic polysulphones containing ketone or aldehyde groups, and process for preparing them BAYER AG (DE) 1987-12-16 EP disclosed
US-4713452-A Process for preparation of azetidinone derivatives OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 1987-12-15 US disclosed
US-4039334-A ORGANIC SILVER SALT AND HALIDE, REDUCING AGENT, ROSIN FUJI PHOTO FILM CO., LTD. (JA) 1977-08-02 US disclosed