Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 3/20 | 0.47 |
| ▸ | CA2 known ✓ | P00918 | 3/20 | 0.47 |
| ▸ | CA12 known ✓ | O43570 | 1/20 | 0.43 |
| ▸ | CA4 known ✓ | P22748 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL6690832 | 0.95 | ALDH1A1 (0.48) | ALDH1A1HSD17B10ACHECA1CA2 | |
| Silver SCHEMBL11302915 | 0.95 | ALDH1A1 (0.48) | ALDH1A1HSD17B10ACHECA1CA2 | |
| Potassium Ion SCHEMBL6693540 | 0.95 | ALDH1A1 (0.48) | ALDH1A1HSD17B10ACHECA1CA2 | |
| SCHEMBL6652423 | 0.77 | CES1 (0.50) | ALDH1A1HSD17B10ACHECA1CA2 | |
| SCHEMBL27909482 | 0.77 | ALDH1A1 (0.72) | ALDH1A1HSD17B10ACHECA1CA2 | |
| SCHEMBL22567 | 0.77 | ALDH1A1 (0.72) | ALDH1A1HSD17B10ACHECA1CA2 | |
| SCHEMBL11302917 | 0.76 | CES1 (0.48) | ALDH1A1HSD17B10ACHECA1CA2 | |
| SCHEMBL6690834 | 0.76 | CES1 (0.48) | ALDH1A1HSD17B10ACHECA1CA2 | |
| SCHEMBL6693542 | 0.76 | CES1 (0.48) | ALDH1A1HSD17B10ACHECA1CA2 | |
| SCHEMBL1584829 | 0.76 | CES1 (0.48) | ALDH1A1HSD17B10ACHECA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9650330-B2 | Process for the synthesis of aryl sulfones | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2017-05-16 | — | — | US | claimed |
| US-20160304447-A1 | A PROCESS FOR THE SYNTHESIS OF ARYL SULFONES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-10-20 | — | — | US | claimed |
| WO-2015087352-A1 | A PROCESS FOR THE SYNTHESIS OF ARYL SULFONES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2015-06-18 | — | — | WO | claimed |
| CN-122031506-A | Chiral control | 波涛生命科学有限公司 | 2026-05-15 | — | — | CN | disclosed |
| CN-120060869-A | Electrocatalytic synthesis method of aryl sulfone compound | 平顶山学院 | 2025-05-30 | — | — | CN | disclosed |
| WO-2025085848-A1 | ANTIBACTERIAL COMPOUNDS | ARREPATH, INC. (US) | 2025-04-24 | — | — | WO | disclosed |
| US-20240229026-A1 | CHIRAL CONTROL | WAVE LIFE SCIENCES LTD. (SG) | 2024-07-11 | — | — | US | disclosed |
| CN-115490621-B | Preparation method of iodo-bicyclo [1.1.1] pentane derivative | 浙江工业大学 | 2024-06-21 | — | — | CN | disclosed |
| CN-115197108-B | Preparation method of gamma-ketosulfone compound | 南华大学 | 2023-11-28 | — | — | CN | disclosed |
| EP-4219516-A2 | CHIRAL CONTROL | Wave Life Sciences Ltd. (SG) | 2023-08-02 | — | — | EP | disclosed |
| US-11643657-B2 | Chiral control | WAVE LIFE SCIENCES LTD. (SG) | 2023-05-09 | — | — | US | disclosed |
| US-20040034257-A1 | Novel sulfone derivatives and process for producing these | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-02-19 | — | — | US | disclosed |
| EP-1359143-A1 | NOVEL SULFONE DERIVATIVES AND PROCESS FOR PRODUCING THESE | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2003-11-05 | — | — | EP | disclosed |
| EP-1231197-A1 | Process for producing allyl halide compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-08-14 | — | — | EP | disclosed |
| US-20020107422-A1 | Process for producing allyl halide compound | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2002-08-08 | — | — | US | disclosed |
| US-4740596-A | Process for preparation of 4-sulfonylthio azetidinone derivatives | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1988-04-26 | — | — | US | disclosed |
| US-4713452-A | Process for preparation of azetidinone derivatives | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1987-12-15 | — | — | US | disclosed |
| US-4301278-A | BY HYDROGENATION IN THE PRESENCE OF A CATALYST | CIBA-GEIGY CORPORATION (US) | 1981-11-17 | — | — | US | disclosed |
| US-4255328-A | CEPHALOSPORINS | CIBA-GEIGY CORPORATION (US) | 1981-03-10 | — | — | US | disclosed |
| US-4147864-A | Process for the manufacture of 7β-amino-3-cephem-3-ol-4 carboxylic acid compounds | CIBA-GEIGY CORPORATION (US) | 1979-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040034257-A1 | Novel sulfone derivatives and process for producing these | RBP4, ADH4, RARB | CA1 3756/4885CA2 3444/4885CA12 2287/4885 |
| US-20240229026-A1 | CHIRAL CONTROL | RNGTT, POLI, NSUN3 | CA1 467/4885CA2 904/4885CA12 876/4885 |
| US-20160304447-A1 | A PROCESS FOR THE SYNTHESIS OF ARYL SULFONES | ARSA, TPST2, STS | CA1 3612/4885CA2 1552/4885CA12 2293/4885 |
| US-11643657-B2 | Chiral control | RNGTT, POLI, NSUN3 | CA1 467/4885CA2 904/4885CA12 876/4885 |
| US-20020107422-A1 | Process for producing allyl halide compound | ENY2, ZYX, RPS4Y1 | CA1 4462/4885CA2 4250/4885CA12 4498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.