Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 2/20 | 0.53 |
| ▸ | DRD3 | P35462 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 6/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6650930 | 0.98 | HRH4 (0.58) | HRH4DRD2DRD3L3MBTL1TSHR | |
| Hydrochloric Acid SCHEMBL6652672 | 0.97 | HRH4 (0.57) | HRH4DRD2DRD3L3MBTL1TSHR | |
| Hypochlorous Acid SCHEMBL6651063 | 0.81 | MAPT (0.51) | HCRTR1HCRTR2CA12CA1CA2 | |
| Hypochlorous Acid SCHEMBL7712000 | 0.81 | RECQL (0.49) | TSHRHCRTR1HCRTR2ALDH1A1HPGD | |
| Hypochlorous Acid SCHEMBL6652746 | 0.81 | ALDH1A1 (0.67) | L3MBTL1HCRTR1HCRTR2ALDH1A1MAPT | |
| Hypochlorous Acid SCHEMBL6654575 | 0.80 | ALDH1A1 (0.72) | HCRTR1HCRTR2ALDH1A1MAPTLMNA | |
| SCHEMBL6651339 | 0.80 | MAPT (0.52) | HCRTR1HCRTR2CA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL6651061 | 0.79 | MAPT (0.51) | HCRTR1HCRTR2CA12CA1CA2 | |
| SCHEMBL6655479 | 0.79 | ALDH1A1 (0.74) | HCRTR1HCRTR2ALDH1A1MAPTLMNA | |
| SCHEMBL6650909 | 0.79 | ALDH1A1 (0.70) | L3MBTL1HCRTR1HCRTR2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1006110-B1 | DERIVATIVES OF ACYL-PIPERAZINIL-PYRIMIDINS, PREPARATION THEREOF AND APPLICATION AS MEDICAMENTS | ESTEVE LABOR DR (ES) | 2004-02-11 | — | — | EP | claimed |
| US-6372746-B1 | ANTICONVULSIVE AGENTS, SEDATIVES AND EATING DISORDERS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2002-04-16 | — | — | US | claimed |
| EP-1006110-A1 | DERIVATIVES OF ACYL-PIPERAZINIL-PYRIMIDINS, PREPARATION THEREOF AND APPLICATION AS MEDICAMENTS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2000-06-07 | — | — | EP | claimed |