Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.72 |
| ▸ | LMNA | P02545 | 3/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 9/20 | 0.47 |
| ▸ | HCRTR2 | O43614 | 9/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.43 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.43 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6655479 | 0.99 | ALDH1A1 (0.74) | ALDH1A1LMNAKMT2ACYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL6654568 | 0.98 | ALDH1A1 (0.72) | ALDH1A1LMNAKMT2ACYP1A2CYP3A4 | |
| Hypochlorous Acid SCHEMBL6652676 | 0.80 | HRH4 (0.56) | ALDH1A1LMNAHPGDHCRTR1HCRTR2 | |
| Hypochlorous Acid SCHEMBL6652392 | 0.79 | HCRTR1 (0.44) | ALDH1A1LMNAKMT2AHPGDHCRTR1 | |
| SCHEMBL6650930 | 0.78 | HRH4 (0.58) | ALDH1A1HPGDHCRTR1HCRTR2RECQL | |
| SCHEMBL6652566 | 0.78 | HCRTR1 (0.45) | ALDH1A1LMNAKMT2AHPGDHCRTR1 | |
| Hypochlorous Acid SCHEMBL6651063 | 0.78 | MAPT (0.51) | ALDH1A1LMNAKMT2AHPGDHCRTR1 | |
| Hydrochloric Acid SCHEMBL6652672 | 0.77 | HRH4 (0.57) | ALDH1A1HPGDHCRTR1HCRTR2RECQL | |
| Hypochlorous Acid SCHEMBL6650991 | 0.77 | HCRTR1 (0.48) | ALDH1A1LMNAHPGDHCRTR1HCRTR2 | |
| Hydrochloric Acid SCHEMBL6652387 | 0.77 | HCRTR1 (0.44) | ALDH1A1LMNAKMT2AHPGDHCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1006110-B1 | DERIVATIVES OF ACYL-PIPERAZINIL-PYRIMIDINS, PREPARATION THEREOF AND APPLICATION AS MEDICAMENTS | ESTEVE LABOR DR (ES) | 2004-02-11 | — | — | EP | claimed |
| US-6372746-B1 | ANTICONVULSIVE AGENTS, SEDATIVES AND EATING DISORDERS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2002-04-16 | — | — | US | claimed |
| EP-1006110-A1 | DERIVATIVES OF ACYL-PIPERAZINIL-PYRIMIDINS, PREPARATION THEREOF AND APPLICATION AS MEDICAMENTS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2000-06-07 | — | — | EP | claimed |