SCHEMBL6652839

SCHEMBL6652839

O=C1c2ccccc2C(=O)c2c(F)c(Nc3c(Cl)cccc3Cl)c(Nc3c(Cl)cccc3Cl)c(F)c21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 2/20 0.41
MAPT P10636 3/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
MAOA P21397 1/20 0.40
IDO1 P14902 1/20 0.39
DNMT1 P26358 1/20 0.39
DNMT3L Q9UJW3 1/20 0.39
DNMT3A Q9Y6K1 1/20 0.39
DHODH Q02127 2/20 0.39
STK10 O94804 1/20 0.39
SLK Q9H2G2 1/20 0.39
MAPK1 P28482 2/20 0.38
RAB9A P51151 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
LMNA P02545 2/20 0.38
EGFR P00533 1/20 0.38
PABPC1 P11940 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6653744 0.94 ADORA2A (0.39) ADORA2AMAPTMEN1KMT2AMAOA
SCHEMBL6682946 0.90 DHODH (0.43) ADORA2AMAPTMEN1KMT2ADHODH
SCHEMBL22283454 0.89 TOP2A (0.41) ADORA2AMAPTMEN1KMT2AMAOA
SCHEMBL6652563 0.87 MAPT (0.36) ADORA2AMAPTMEN1KMT2AMAOA
SCHEMBL6651442 0.84 DHODH (0.42) ADORA2AMAPTMEN1KMT2ADHODH
SCHEMBL6653262 0.84 ADORA2A (0.39) ADORA2AMAPTMEN1KMT2AMAOA
SCHEMBL6652245 0.84 GAA (0.38) MAPTMEN1KMT2AMAPK1LMNA
SCHEMBL22493007 0.83 TOP2A (0.39) ADORA2AMAPTMEN1KMT2AMAOA
SCHEMBL6651924 0.82 CXCL8 (0.38) ADORA2AMAPTDHODHSTK10SLK
SCHEMBL7933254 0.82 MAPT (0.39) MAPTMEN1KMT2AMAOAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0833203-B1 Anthraquinone compounds NIPPON CATALYTIC CHEM IND (JP) 2004-06-16 EP disclosed
US-5968688-A RESINS AND DYES FOR COLOR FILTERS NIPPON SHOKUBAI CO., LTD. (JP) 1999-10-19 US disclosed
EP-0833203-A1 Color filter grade photosensitive resin coloring composition, and color filter using the same NIPPON SHOKUBAI CO., LTD. (JP) 1998-04-01 EP disclosed