SCHEMBL7933254

SCHEMBL7933254

O=C1c2c(O)ccc(O)c2C(=O)c2c(F)c(Nc3c(Cl)cccc3Cl)c(Nc3c(Cl)cccc3Cl)c(F)c21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.39
MAOA P21397 4/20 0.39
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
HPGD P15428 3/20 0.38
TSHR P16473 3/20 0.38
CSNK2A2 P19784 3/20 0.38
CSNK2B P67870 3/20 0.38
CSNK2A1 P68400 3/20 0.38
CSNK2A3 Q8NEV1 3/20 0.38
ALDH1A1 P00352 3/20 0.38
ALOX15 P16050 3/20 0.38
HSD17B10 Q99714 3/20 0.38
TDP1 Q9NUW8 3/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
LMNA P02545 2/20 0.38
MAPK1 P28482 2/20 0.38
MAOB P27338 1/20 0.38
HTT P42858 1/20 0.38
CYP3A4 P08684 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7921338 0.94 MAPT (0.37) MAPTMAOAMEN1KMT2AHPGD
SCHEMBL7929769 0.90 PTGS2 (0.41) EGFRPIM1GAACXCL8PTGS2
SCHEMBL7927149 0.86 PTGS2 (0.39) GAACXCL8PTGS2
SCHEMBL7921280 0.86 EGFR (0.45) MAPTMAOAMEN1KMT2AEGFR
SCHEMBL7933236 0.84 PTGS2 (0.40) GAACXCL8PTGS2
SCHEMBL7928319 0.83 KMT2A (0.41) MAPTMAOAMEN1KMT2AHPGD
SCHEMBL7921192 0.83 CA12 (0.37) MAPTMAOAMEN1KMT2AALDH1A1
SCHEMBL7927152 0.83 MEN1 (0.40) MAPTMAOAMEN1KMT2ATDP1
SCHEMBL7929957 0.83 LMNA (0.38) MAPTMAOAMEN1KMT2AHPGD
SCHEMBL7928272 0.82 ELANE (0.34) MAPTMEN1KMT2AALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0661350-B1 Quinizarin compound, method for production thereof, and use therefor NIPPON CATALYTIC CHEM IND (JP) 2001-08-22 EP disclosed
US-5817843-A Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1998-10-06 US disclosed
US-5608091-A SHEETS FOR HEAT EXCHANGING AND OPTICAL RECORDING MATERIAL NIPPON SHOKUBAI CO., LTD. (JP) 1997-03-04 US disclosed
EP-0661350-A1 Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1995-07-05 EP disclosed