⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10949083 | 0.91 | RECQL (0.41) | — | |
| SCHEMBL10952382 | 0.91 | RECQL (0.41) | — | |
| SCHEMBL8642408 | 0.69 | PABPC1 (0.31) | — | |
| SCHEMBL14714256 | 0.69 | PABPC1 (0.38) | — | |
| SCHEMBL13780078 | 0.67 | HPGD (0.43) | — | |
| SCHEMBL4917509 | 0.63 | TSHR (0.39) | — | |
| SCHEMBL3127470 | 0.62 | TSHR (0.42) | — | |
| SCHEMBL672953 | 0.60 | — | — | |
| SCHEMBL10985073 | 0.60 | SIGMAR1 (0.48) | — | |
| SCHEMBL439119 | 0.57 | TSHR (0.71) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244763-A4 | ADDITIVE COMPOSITION | LUBRIZOL CORP (US) | 2004-05-06 | — | — | EP | disclosed |
| EP-1244763-A1 | ADDITIVE COMPOSITION | THE LUBRIZOL CORPORATION (US) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001038462-A1 | ADDITIVE COMPOSITION | THE LUBRIZOL CORPORATION (US) | 2001-05-31 | — | — | WO | disclosed |
| US-6224642-B1 | A FUEL ADDITIVE FOR REDUCING THE WEAR OF INTERNAL COMBUSTION ENGINE CONSISTS OF A HYDROXY HYDROCARBYL AND HYDROXYPROPYLAMINE MODIFIED POLYOXYBUTYLENE GLYCOL; A COMPOUND SELECTED FROM FATTY ACID, AMIDE, ESTER, ETC. | THE LUBRIZOL CORPORATION | 2001-05-01 | — | — | US | disclosed |