Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA4 | P22748 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | CTSG | P08311 | 1/20 | 0.45 |
| ▸ | CMA1 | P23946 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7121380 | 0.85 | L3MBTL1 (0.59) | ALDH1A1KMT2ACA1CA2CA4 | |
| SCHEMBL7121377 | 0.85 | L3MBTL1 (0.59) | ALDH1A1KMT2ACA1CA2CA4 | |
| SCHEMBL4298802 | 0.85 | MMP2 (0.46) | MMP2ALDH1A1HSP90AA1KMT2ATDP1 | |
| SCHEMBL4298798 | 0.85 | MMP2 (0.46) | MMP2ALDH1A1HSP90AA1KMT2ATDP1 | |
| SCHEMBL1596115 | 0.84 | MMP2 (0.46) | MMP2ALDH1A1MAPK1LMNATDP1 | |
| SCHEMBL1596117 | 0.84 | MMP2 (0.46) | MMP2ALDH1A1MAPK1LMNATDP1 | |
| SCHEMBL3832921 | 0.82 | NPSR1 (0.55) | ALDH1A1LMNAMAPTSMN1; SMN2CA1 | |
| SCHEMBL3832918 | 0.82 | NPSR1 (0.55) | ALDH1A1LMNAMAPTSMN1; SMN2CA1 | |
| SCHEMBL7127867 | 0.82 | CA1 (0.50) | ALDH1A1KMT2ACA1CA2CA4 | |
| SCHEMBL7127875 | 0.82 | CA1 (0.50) | ALDH1A1KMT2ACA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235797-B1 | ARALKYL-1,2-DIAMINES HAVING CALCIMIMETIC ACTIVITY AND PREPARATION MODE | CENTRE NAT RECH SCIENT (FR) | 2004-06-09 | — | — | EP | claimed |
| EP-1235797-A1 | ARALKYL-1,2-DIAMINES HAVING CALCIMIMETIC ACTIVITY AND PREPARATION MODE | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2002-09-04 | — | — | EP | claimed |
| WO-2001034562-A1 | ARALKYL-1,2-DIAMINES HAVING CALCIMIMETIC ACTIVITY AND PREPARATION MODE | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2001-05-17 | — | — | WO | claimed |
| EP-1235797-B1 | ARALKYL-1,2-DIAMINES HAVING CALCIMIMETIC ACTIVITY AND PREPARATION MODE | CENTRE NAT RECH SCIENT (FR) | 2004-06-09 | — | — | EP | disclosed |
| EP-1235797-A1 | ARALKYL-1,2-DIAMINES HAVING CALCIMIMETIC ACTIVITY AND PREPARATION MODE | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001034562-A1 | ARALKYL-1,2-DIAMINES HAVING CALCIMIMETIC ACTIVITY AND PREPARATION MODE | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2001-05-17 | — | — | WO | disclosed |