Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.37 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5779487 | 0.73 | F10 (0.45) | F10ACKR3MEN1NPC1RAB9A | |
| SCHEMBL5779884 | 0.71 | F10 (0.40) | F10ACKR3MEN1NPC1RAB9A | |
| SCHEMBL5783337 | 0.71 | F10 (0.43) | F10ACKR3MEN1NPC1RAB9A | |
| SCHEMBL5784009 | 0.63 | F10 (0.39) | F10MEN1NPC1RAB9AKMT2A | |
| SCHEMBL5782214 | 0.63 | F10 (0.70) | F10ACKR3MEN1KMT2AALDH1A1 | |
| SCHEMBL5780091 | 0.60 | F10 (0.48) | F10ACKR3MEN1KMT2AALDH1A1 | |
| SCHEMBL3155079 | 0.59 | F10 (0.70) | F10 | |
| SCHEMBL6218284 | 0.59 | GAA (0.47) | F10MEN1NPC1RAB9AKMT2A | |
| SCHEMBL5343307 | 0.59 | MEN1 (0.53) | MEN1NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL186800 | 0.59 | MEN1 (0.53) | MEN1NPC1RAB9AKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1408962-A1 | SUBSTITUTED ISOINDOLES AND THE USE THEREOF | Bayer HealthCare AG (DE) | 2004-04-21 | — | — | EP | disclosed |
| WO-2003007942-A1 | SUBSTITUTED ISOINDOLES AND THE USE THEREOF | BAYER HEALTHCARE AG (DE) | 2003-01-30 | — | — | WO | disclosed |