Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TDP2 | O95551 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2896689 | 0.77 | POLB (0.56) | MAPK1ALDH1A1LMNAMEN1THRA | |
| SCHEMBL2900768 | 0.72 | LMNA (0.49) | MAPK1ALDH1A1LMNAPOLBGAA | |
| SCHEMBL6656251 | 0.69 | MAPK1 (0.33) | MAPK1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL6654131 | 0.69 | — | — | |
| SCHEMBL292949 | 0.69 | MAPK1 (0.51) | MAPK1ALDH1A1LMNAMEN1THRA | |
| SCHEMBL145468 | 0.67 | TP53 (0.67) | ALDH1A1LMNAMEN1THRBKMT2A | |
| SCHEMBL6656212 | 0.67 | HCAR3 (0.41) | MAPK1ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL28316734 | 0.67 | TSHR (0.49) | ALDH1A1POLBGAAHTTKDM4E | |
| SCHEMBL6313462 | 0.66 | CYP2C19 (0.45) | ALDH1A1POLBKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL1452105 | 0.66 | MDM4 (0.49) | ALDH1A1LMNAMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1430019-A1 | SPHINGOLIPIDS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2004-06-23 | — | — | EP | disclosed |
| WO-2003027058-A1 | SPHINGOLIPIDS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2003-04-03 | — | — | WO | disclosed |
| WO-2001079152-A1 | SPHINGOLIPIDS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2001-10-25 | — | — | WO | disclosed |