Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 10/20 | 0.48 |
| ▸ | PPARG | P37231 | 9/20 | 0.48 |
| ▸ | FPR2 | P25090 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 4/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4334868 | 0.89 | IDH1 (0.42) | PPARAPPARGFPR2ALDH1A1MEN1 | |
| SCHEMBL4328261 | 0.86 | MGLL (0.53) | PPARAPPARGFPR2MEN1KMT2A | |
| SCHEMBL4341815 | 0.84 | FPR2 (0.45) | PPARAPPARGFPR2PPARDMGLL | |
| SCHEMBL4338925 | 0.81 | PPARG (0.55) | PPARAPPARGALDH1A1PPARD | |
| SCHEMBL13819764 | 0.81 | MAOB (0.57) | PPARAPPARGPPARD | |
| SCHEMBL4334192 | 0.81 | MGLL (0.60) | PPARAPPARGPPARDMGLL | |
| SCHEMBL4347142 | 0.79 | MEN1 (0.52) | PPARAPPARGFPR2MEN1KMT2A | |
| SCHEMBL4334181 | 0.79 | MEN1 (0.52) | PPARAPPARGFPR2MEN1KMT2A | |
| SCHEMBL4346891 | 0.79 | PPARG (0.51) | PPARAPPARGPPARD | |
| SCHEMBL4335055 | 0.78 | SMN1; SMN2 (0.52) | PPARAPPARGLMNAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1380562-A1 | CARBOXYLIC ACID DERIVATIVE AND SALT THEREOF | Eisai Co., Ltd. (JP) | 2004-01-14 | — | — | EP | disclosed |