Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 4/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ADH1B | P00325 | 1/20 | 0.33 |
| ▸ | ADH1C | P00326 | 1/20 | 0.33 |
| ▸ | ADH1A | P07327 | 1/20 | 0.33 |
| ▸ | ADH4 | P08319 | 1/20 | 0.33 |
| ▸ | ADH7 | P40394 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.32 |
| ▸ | GAPDH | P04406 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26437943 | 1.00 | TSHR (0.48) | TSHRSMN1; SMN2CTSKDNM1ALDH1A1 | |
| SCHEMBL20411572 | 1.00 | TSHR (0.48) | TSHRSMN1; SMN2CTSKDNM1ALDH1A1 | |
| SCHEMBL16592070 | 1.00 | TSHR (0.48) | TSHRSMN1; SMN2CTSKDNM1ALDH1A1 | |
| SCHEMBL1915006 | 0.91 | ADH1B (0.44) | TSHRSMN1; SMN2DNM1ADH1BADH1C | |
| SCHEMBL21621642 | 0.85 | — | — | |
| SCHEMBL7677657 | 0.85 | — | — | |
| SCHEMBL14660213 | 0.83 | TSHR (0.50) | TSHRSMN1; SMN2CTSKDNM1ALDH1A1 | |
| SCHEMBL12335640 | 0.77 | CHRM2 (0.34) | — | |
| SCHEMBL14877997 | 0.77 | CHRM2 (0.34) | — | |
| SCHEMBL26541492 | 0.77 | CYP2C19 (0.43) | TSHRALDH1A1ADH1BADH1CADH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230132372-A9 | REAGENTS FOR QUANTITATIVE MASS SPECTROMETRY | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-04-27 | — | — | US | disclosed |
| US-20220018847-A1 | REAGENTS FOR QUANTITATIVE MASS SPECTROMETRY | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2022-01-20 | — | — | US | disclosed |
| US-20200174007-A1 | REAGENTS FOR QUANTITATIVE MASS SPECTROMETRY | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-06-04 | — | — | US | disclosed |
| US-20180209985-A1 | REAGENTS FOR QUANTITATIVE MASS SPECTROMETRY | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-07-26 | — | — | US | disclosed |
| WO-2016196994-A9 | REAGENTS FOR QUANTITATIVE MASS SPECTROMETRY | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-03-02 | — | — | WO | disclosed |
| EP-1423353-A1 | SUBSTITUTED OCTAHYDROPHENANTHRENE COMPOUNDS AND THEIR USE AS NMDA ANTAGONISTS | Grünenthal GmbH (DE) | 2004-06-02 | — | — | EP | disclosed |
| WO-2003016261-A1 | SUBSTITUTED OCTAHYDROPHENANTHRENE COMPOUNDS AND THEIR USE AS NMDA ANTAGONISTS | Grünenthal GmbH (DE) | 2003-02-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200174007-A1 | REAGENTS FOR QUANTITATIVE MASS SPECTROMETRY | CHAMP1, SRMS, QPCTL | TSHR 3110/4885SMN1; SMN2 1861/4885CTSK 3113/4885 |
| US-20230132372-A9 | REAGENTS FOR QUANTITATIVE MASS SPECTROMETRY | CHAMP1, SRMS, QPCTL | TSHR 3110/4885SMN1; SMN2 1861/4885CTSK 3113/4885 |
| US-20180209985-A1 | REAGENTS FOR QUANTITATIVE MASS SPECTROMETRY | CHAMP1, SRMS, QPCTL | TSHR 3110/4885SMN1; SMN2 1861/4885CTSK 3113/4885 |
| US-20220018847-A1 | REAGENTS FOR QUANTITATIVE MASS SPECTROMETRY | CHAMP1, SRMS, QPCTL | TSHR 3110/4885SMN1; SMN2 1861/4885CTSK 3113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.