Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.31 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.31 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2952373 | 0.82 | — | — | |
| SCHEMBL21633983 | 0.78 | GBA1 (0.33) | ESR1CYP3A4CYP2C9ESR2METAP1 | |
| SCHEMBL9815717 | 0.78 | ESR2 (0.41) | ESR1CYP3A4CYP2C9ESR2 | |
| SCHEMBL7429602 | 0.77 | METAP1 (0.50) | METAP1 | |
| Glycerin SCHEMBL9652881 | 0.76 | LMNA (0.53) | ESR1CYP3A4CYP2C9ESR2 | |
| Glycerin SCHEMBL8737333 | 0.76 | LMNA (0.53) | ESR1CYP3A4CYP2C9ESR2 | |
| SCHEMBL1678958 | 0.75 | — | — | |
| SCHEMBL130642 | 0.74 | ESR2 (0.46) | ESR1CYP3A4CYP2C9ESR2 | |
| SCHEMBL1316560 | 0.74 | ESR2 (0.46) | ESR1CYP3A4CYP2C9ESR2 | |
| SCHEMBL2267415 | 0.74 | ESR2 (0.46) | ESR1CYP3A4CYP2C9ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140787-B1 | CROSSLINKERS BASED ON DIBENZALACETONE DERIVATIVES | EASTMAN CHEM CO (US) | 2004-07-28 | — | — | EP | claimed |
| EP-1140787-B1 | CROSSLINKERS BASED ON DIBENZALACETONE DERIVATIVES | EASTMAN CHEM CO (US) | 2004-07-28 | — | — | EP | disclosed |
| US-6194615-B1 | USEFUL AS CROSSLINKERS IN COATINGS APPLICATIONS | EASTMAN CHEMICAL COMPANY | 2001-02-27 | — | — | US | disclosed |