Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.30 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.30 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22919271 | 0.85 | PRKCA (0.33) | — | |
| SCHEMBL13672365 | 0.81 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL27255916 | 0.81 | HSD17B10 (0.33) | HSD17B10 | |
| SCHEMBL17206868 | 0.81 | HSD17B10 (0.55) | HSD17B10LPAR1LPAR3LPAR2 | |
| SCHEMBL21539301 | 0.81 | HSD17B10 (0.32) | HSD17B10LPAR1LPAR3LPAR2 | |
| SCHEMBL13672332 | 0.78 | TSHR (0.41) | CYP3A4LPAR1LPAR3LPAR2 | |
| SCHEMBL13672304 | 0.78 | PRKCA (0.30) | — | |
| SCHEMBL27268289 | 0.76 | CYP3A4 (0.38) | CYP3A4ALDH1A1 | |
| SCHEMBL358536 | 0.76 | MEN1 (0.45) | CYP3A4ALDH1A1 | |
| SCHEMBL3308426 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1471940-A2 | INACTIVATION OF WEST NILE VIRUS AND PLASMODIUM FALCIPARUM USING ALLOXAZINE-DERIVATING PHOTOSENSITISERS | Gambro, Inc. (US) | 2004-11-03 | — | — | EP | disclosed |
| WO-2002055021-A9 | GLYCOPOLYMERS AND FREE RADICAL POLYMERIZATION METHODS | UNIV EMORY (US) | 2004-01-29 | — | — | WO | disclosed |
| WO-2003063902-A2 | INACTIVATION OF WEST NILE VIRUS AND PLASMODIUM FALCIPARUM USING ALLOXAZINE-DERIVATING PHOTOSENSITIZERS | GAMBRO, INC. (US) | 2003-08-07 | — | — | WO | disclosed |
| WO-2003057253-A1 | OXYGEN-ENHANCED PATHOGEN INACTIVATION | GAMBRO, INC. (US) | 2003-07-17 | — | — | WO | disclosed |