SCHEMBL6654879

SCHEMBL6654879

CC(O)CN(C1CC(C)CCC1C(C)C)C1CC(C)CCC1C(C)C

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TRPM8 Q7Z2W7 3/20 0.47
TRPA1 O75762 2/20 0.47
EPHX1 P07099 3/20 0.41
ALDH1A1 P00352 2/20 0.40
LMNA P02545 1/20 0.36
CYP19A1 P11511 2/20 0.35
KDM4E B2RXH2 1/20 0.35
APOBEC3A P31941 1/20 0.35
APOBEC3G Q9HC16 1/20 0.35
GAA P10253 1/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
OPRM1 P35372 1/20 0.33
TRPV1 Q8NER1 2/20 0.32
KCNA5 P22460 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31105805 0.82 TRPM8 (0.48) TRPM8TRPA1EPHX1ALDH1A1LMNA
SCHEMBL5307491 0.80 TRPM8 (0.47) TRPM8TRPA1EPHX1ALDH1A1LMNA
SCHEMBL5680417 0.79 TRPM8 (0.47) TRPM8TRPA1EPHX1ALDH1A1LMNA
SCHEMBL2285485 0.79 TRPM8 (0.46) TRPM8TRPA1EPHX1ALDH1A1LMNA
SCHEMBL3702361 0.77 EPHX1 (0.46) TRPM8TRPA1EPHX1ALDH1A1CYP19A1
SCHEMBL6335743 0.77 TRPM8 (0.52) TRPM8TRPA1EPHX1ALDH1A1LMNA
Hydrochloric Acid SCHEMBL27721782 0.75 TRPM8 (0.42) TRPM8TRPA1EPHX1ALDH1A1LMNA
SCHEMBL28354413 0.74 TRPM8 (0.48) TRPM8TRPA1EPHX1ALDH1A1LMNA
SCHEMBL15435867 0.74 TRPM8 (0.52) TRPM8TRPA1EPHX1ALDH1A1LMNA
SCHEMBL26355350 0.74 TRPM8 (0.52) TRPM8TRPA1EPHX1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1330502-B1 COATING COMPOSITION VALSPAR SOURCING INC (US) 2004-06-02 EP disclosed
EP-1330502-A2 COATING COMPOSITION Valspar Sourcing, Inc. (US) 2003-07-30 EP disclosed
US-6509417-B1 Automobile finishes and paints LILLY INDUSTRIES, INC. 2003-01-21 US disclosed
WO-2002036692-A2 COATING COMPOSITION VALSPAR SOURCING, INC. (US) 2002-05-10 WO disclosed
EP-0355959-B1 MULTI-COMPONENT COATING COMPOSITION COMPRISING AN ANHYDRIDE CONTAINING POLYMER, A GLYCIDYL COMPONENT AND A MONOMERIC OR OLIGOMERIC ANHYDRIDE COMPONENT E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-10-06 EP disclosed
EP-0351966-B1 MULTI-COMPONENT COATING COMPOSITION COMPRISING AN ANHYDRIDE CONTAINING POLYMER, A GLYCIDYL COMPONENT AND A SELF-STABILIZED DISPERSION RESIN E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-09-29 EP disclosed
EP-0355043-B1 MULTI-COMPONENT COATING COMPOSITION COMPRISING AN ANHYDRIDE CONTAINING POLYMER, A GLYCIDYL COMPONENT AND A PHOSPHONIUM CATALYST E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-01-20 EP disclosed
EP-0358306-B1 MULTI-COMPONENT COATING COMPOSITION COMPRISING AN ANHYDRIDE CONTAINING POLYMER, A GLYCIDYL COMPONENT AND A POLYMER WITH MULTIPLE HYDROXYL GROUPS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-09-02 EP disclosed
US-5093391-A Hard, glossy finishes for automobiles and trucks E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-03-03 US disclosed
US-5068153-A Substrate coated with a multilayer coating for automobiles E. I. DU PONT DE NEMOURS AND COMPANY (US) 1991-11-26 US disclosed
US-5057555-A Weatherability, humidity resistance WHITE DONALD A (US) 1991-10-15 US disclosed
US-5017435-A Multi-component coating composition comprising an anhydride containing polymer, a glycidyl component and a monomeric or oligomeric anhydride component E. I. DU PONT DE NEMOURS AND COMPANY (US) 1991-05-21 US disclosed
US-4975474-A FINISHES FOR AUTOMOBILES AND TRUCKS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-12-04 US disclosed
EP-0358306-A1 Multi-component coating composition comprising an anhydride containing polymer, a glycidyl component and a polymer with multiple hydroxyl groups E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-03-14 EP disclosed
US-4908397-A Binder comprising anhydride acrylic polymer, glycidyl component, stabilized dispersed acrylic resin E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-03-13 US disclosed
EP-0355043-A1 Multi-component coating composition comprising an anhydride containing polymer, a glycidyl component and a phosphonium catalyst E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-02-21 EP disclosed
EP-0351966-A1 Multi-component coating composition comprising an anhydride containing polymer, a glycidyl component and a self-stabilized dispersion resin E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-01-24 EP disclosed
EP-0351965-A1 Multi-component coating composition comprising an anhydride containing polymer, a glycidyl component and an acid functional component E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-01-24 EP disclosed
EP-0171019-B1 PROCESS FOR THE PREPARATION OF IF NEED BE CELLULAR POLYURETHANES BAYER AG (DE) 1989-08-16 EP disclosed