Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31105805 | 0.85 | TRPM8 (0.48) | TRPM8TRPA1EPHX1ALDH1A1KCNA5 | |
| SCHEMBL5307491 | 0.83 | TRPM8 (0.47) | TRPM8TRPA1EPHX1ALDH1A1KCNA5 | |
| SCHEMBL6654879 | 0.79 | TRPM8 (0.47) | TRPM8TRPA1EPHX1ALDH1A1KCNA5 | |
| SCHEMBL5680417 | 0.79 | TRPM8 (0.47) | TRPM8TRPA1EPHX1ALDH1A1KCNA5 | |
| Hydrochloric Acid SCHEMBL27721782 | 0.77 | TRPM8 (0.42) | TRPM8TRPA1EPHX1ALDH1A1KCNA5 | |
| SCHEMBL15435867 | 0.76 | TRPM8 (0.52) | TRPM8TRPA1EPHX1ALDH1A1KCNA5 | |
| SCHEMBL26355350 | 0.76 | TRPM8 (0.52) | TRPM8TRPA1EPHX1ALDH1A1KCNA5 | |
| SCHEMBL3383827 | 0.76 | TRPM8 (0.41) | TRPM8TRPA1EPHX1ALDH1A1KCNA5 | |
| SCHEMBL3702361 | 0.76 | EPHX1 (0.46) | TRPM8TRPA1EPHX1ALDH1A1KCNA5 | |
| SCHEMBL6577889 | 0.75 | TRPM8 (0.40) | TRPM8TRPA1EPHX1ALDH1A1KCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7250446-B2 | Mercaptophenyl naphthyl methane compounds and synthesis thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-07-31 | — | — | US | claimed |
| US-20040229869-A1 | Novel mercaptophenyl naphthyl methane compounds and synthesis thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2004-11-18 | — | — | US | claimed |
| US-10653150-B2 | Shelf life and color profile of resin compositions with silver nanoparticles | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2020-05-19 | — | — | US | disclosed |
| US-20190200617-A1 | SHELF LIFE AND COLOR PROFILE OF RESIN COMPOSITIONS WITH SILVER NANOPARTICLES | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2019-07-04 | — | — | US | disclosed |
| US-10251398-B2 | Improving shelf life and color profile of resin compositions with silver nanoparticles | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2019-04-09 | — | — | US | disclosed |
| US-10154669-B2 | Improving color and release profile of resin compositions comprising silver nanoparticles | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2018-12-18 | — | — | US | disclosed |
| US-20160255840-A1 | IMPROVING COLOR AND RELEASE PROFILE OF RESIN COMPOSITIONS COMPRISING SILVER NANOPARTICLES | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2016-09-08 | — | — | US | disclosed |
| US-20160255839-A1 | IMPROVING SHELF LIFE AND COLOR PROFILE OF RESIN COMPOSITIONS WITH SILVER NANOPARTICLES | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2016-09-08 | — | — | US | disclosed |
| US-9125817-B2 | Dual-cure dental resins and adhesives with increased cure and color-stability and low color | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2015-09-08 | — | — | US | disclosed |
| WO-2015051196-A1 | IMPROVING COLOR AND RELEASE PROFILE OF RESIN COMPOSITIONS COMPRISING SILVER NANOPARTICLES | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2015-04-09 | — | — | WO | disclosed |
| WO-2015051194-A1 | IMPROVING SHELF LIFE AND COLOR PROFILE OF RESIN COMPOSITIONS WITH SILVER NANOPARTICLES | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2015-04-09 | — | — | WO | disclosed |
| US-8785514-B2 | Dual-cure dental resins and adhesives with increased cure and color stability and low color | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2014-07-22 | — | — | US | disclosed |
| US-20140141390-A1 | DUAL-CURE DENTAL RESINS AND ADHESIVES WITH INCREASED CURE AND COLOR-STABILITY AND LOW COLOR | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2014-05-22 | — | — | US | disclosed |
| US-20110200973-A1 | Light- and Dual-Cure Dental Resins and Adhesives With Increased Cure and Color Stability and Low Color | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2011-08-18 | — | — | US | disclosed |
| WO-2009073570-A2 | LIGHT- AND DUAL-CURE DENTAL RESINS AND ADHESIVES WITH INCREASED CURE AND COLOR-STABILITY, AND LOW COLOR | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2009-06-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160255839-A1 | IMPROVING SHELF LIFE AND COLOR PROFILE OF RESIN COMPOSITIONS WITH SILVER NANOPARTICLES | MPO, RNGTT, GDA | TRPM8 4611/4885TRPA1 4123/4885EPHX1 1589/4885 |
| US-20190200617-A1 | SHELF LIFE AND COLOR PROFILE OF RESIN COMPOSITIONS WITH SILVER NANOPARTICLES | MPO, RNGTT, GDA | TRPM8 4608/4885TRPA1 4046/4885EPHX1 1777/4885 |
| US-10251398-B2 | Improving shelf life and color profile of resin compositions with silver nanoparticles | MPO, RNGTT, GDA | TRPM8 4611/4885TRPA1 4123/4885EPHX1 1589/4885 |
| US-20160255840-A1 | IMPROVING COLOR AND RELEASE PROFILE OF RESIN COMPOSITIONS COMPRISING SILVER NANOPARTICLES | CD63, GAR1, ARG1 | TRPM8 2749/4885TRPA1 2619/4885EPHX1 1709/4885 |
| US-10653150-B2 | Shelf life and color profile of resin compositions with silver nanoparticles | MPO, RNGTT, GDA | TRPM8 4608/4885TRPA1 4046/4885EPHX1 1777/4885 |
| US-10154669-B2 | Improving color and release profile of resin compositions comprising silver nanoparticles | CD63, GAR1, ARG1 | TRPM8 2749/4885TRPA1 2619/4885EPHX1 1709/4885 |
| US-20040229869-A1 | Novel mercaptophenyl naphthyl methane compounds and synthesis thereof | BRCA1, PGR, APC | TRPM8 1803/4885TRPA1 2526/4885EPHX1 2615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.