Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11569294 | 0.70 | TRPA1 (0.44) | TRPA1 | |
| SCHEMBL29116644 | 0.68 | TRPA1 (0.46) | TRPA1 | |
| SCHEMBL5637470 | 0.68 | TRPA1 (0.46) | TRPA1 | |
| SCHEMBL27621756 | 0.67 | TRPA1 (0.44) | TRPA1 | |
| SCHEMBL28116479 | 0.65 | TRPA1 (0.42) | TRPA1 | |
| SCHEMBL27460419 | 0.65 | TRPA1 (0.42) | TRPA1 | |
| SCHEMBL27301706 | 0.64 | TRPA1 (0.38) | TRPA1 | |
| SCHEMBL27678770 | 0.62 | TRPA1 (0.37) | TRPA1 | |
| SCHEMBL27432697 | 0.62 | TRPA1 (0.37) | TRPA1 | |
| SCHEMBL12595952 | 0.60 | TRPA1 (0.49) | TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1427713-A1 | BENZOTHIAZEPINE DERIVATIVES FOR THE TREATMENT OF HYPERLIPIDEMIA | Astrazeneca AB (SE) | 2004-06-16 | — | — | EP | disclosed |
| WO-2003022825-A1 | BENZOTHIAZEPINE DERIVATIVES FOR THE TREATMENT OF HYPERLIPIDEMIA | ASTRAZENECA AB (SE) | 2003-03-20 | — | — | WO | disclosed |