Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 8/20 | 0.38 |
| ▸ | HTT | P42858 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL428191 | 0.84 | PIK3CA (0.42) | KMT2AMAPTRAB9APIK3CAPIK3CB | |
| SCHEMBL6653939 | 0.77 | MIF (0.40) | MEN1CYP1A2KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL18924655 | 0.77 | MIF (0.40) | MEN1CYP1A2KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL6656648 | 0.77 | MIF (0.40) | MEN1CYP1A2KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL14661259 | 0.74 | AAK1 (0.37) | — | |
| SCHEMBL7671800 | 0.72 | MAOB (0.44) | ALDH1A1KDM4E | |
| SCHEMBL7671794 | 0.72 | MAOB (0.44) | ALDH1A1KDM4E | |
| SCHEMBL9411226 | 0.71 | MAOB (0.39) | KMT2AMAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL14661318 | 0.70 | — | — | |
| SCHEMBL95448 | 0.69 | MMP12 (0.51) | MEN1CYP1A2CYP2C9KMT2AMMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846691-B1 | Process for preparation of 3-(1-hydroxyphenyl-1-alkoximinomethyl)dioxazines | BAYER CROPSCIENCE AG (DE) | 2004-06-30 | — | — | EP | disclosed |
| US-6437153-B1 | O-HYDROXYETHYL-O'-ALKYLBENZOFURANDIONE DIOXIMES REARRANGED IN THE PRESENCE OF A DILENT, AN ACID OR A BASE; FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-08-20 | — | — | US | disclosed |
| US-20020049319-A1 | O-hydroxyethyl-o'-alkylbenzofurandione dioximes rearranged in the presence of a dilent, an acid or a base; fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2002-04-25 | — | — | US | disclosed |
| US-6335454-B1 | FUNGICIDE INTERMEDIATES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-01-01 | — | — | US | disclosed |
| US-6093837-A | INTERMEDIATES FOR PREPARING COMPOUNDS HAVING FUNGICIDAL PROPERTIES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-07-25 | — | — | US | disclosed |
| US-6005104-A | INTERMEDIATES FOR PREPARING COMPOUNDS HAVING FUNGICIDAL PROPERTIES; PREPARED BY REARRANGING O-HYDROXYETHYL-O'-ALKYL-BENZOFURANDIONE DIOXIMES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |
| EP-0846691-A1 | Process for preparation of 3-(1-hydroxyphenyl-1-alkoximinomethyl)dioxazines | BAYER AG (DE) | 1998-06-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020049319-A1 | O-hydroxyethyl-o'-alkylbenzofurandione dioximes rearranged in the presence of a dilent, an acid or a base; fungicides | DDT, CYP4Z1, CYP51A1 | MEN1 3691/4885CYP1A2 18/4885CYP2C9 29/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.