SCHEMBL665598

SCHEMBL665598

Oc1cc(Cl)ccc1-c1ccc(Cl)cc1Cl

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 5/20 0.61
TSHR P16473 4/20 0.61
ALDH1A1 P00352 4/20 0.61
CYP3A4 P08684 4/20 0.61
TDP1 Q9NUW8 1/20 0.61
AHR P35869 1/20 0.52
HPGD P15428 5/20 0.52
HSP90AA1 P07900 4/20 0.52
LMNA P02545 2/20 0.52
MAPT P10636 2/20 0.52
HSPA5 P11021 2/20 0.52
NR1I2 O75469 1/20 0.52
TTR P02766 1/20 0.52
PGR P06401 1/20 0.52
ADORA3 P0DMS8 1/20 0.52
CBR1 P16152 1/20 0.52
TBXA2R P21731 1/20 0.52
SLC6A2 P23975 1/20 0.52
AGTR1 P30556 1/20 0.52
SLC6A3 Q01959 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL7522925 0.98 HSD17B10 (0.58) HSD17B10TSHRALDH1A1CYP3A4TDP1
SCHEMBL339112 0.89 HSD17B10 (0.65) HSD17B10TSHRALDH1A1CYP3A4TDP1
SCHEMBL21177792 0.87 HSD17B10 (0.52) HSD17B10TSHRALDH1A1CYP3A4TDP1
SCHEMBL29624840 0.87 AHR (0.64) HSD17B10TSHRALDH1A1CYP3A4TDP1
SCHEMBL464507 0.87 AHR (0.64) HSD17B10TSHRALDH1A1CYP3A4TDP1
SCHEMBL13907547 0.85 TSHR (0.50) HSD17B10TSHRALDH1A1CYP3A4TDP1
Ether SCHEMBL2015800 0.84 TSHR (0.45) HSD17B10TSHRALDH1A1CYP3A4TDP1
SCHEMBL11090674 0.81 HSD17B10 (0.56) HSD17B10TSHRALDH1A1CYP3A4TDP1
SCHEMBL16720300 0.80 HSD17B10 (0.45) HSD17B10TSHRALDH1A1CYP3A4TDP1
SCHEMBL11648873 0.79 TSHR (0.48) HSD17B10TSHRALDH1A1CYP3A4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021139193-A1 SUSTAINED-RELEASE LONG-LASTING ANTIBACTERIAL HAND SANITIZER AND PREPARATION METHOD THEREFOR 浙江神英科技股份有限公司 2021-07-15 WO claimed
EP-2308565-A2 ORAL CARE COMPOSITIONS CONTAINING FREE-B-RING FLAVONOIDS AND FLAVANS Colgate-Palmolive Company (US) 2011-04-13 EP claimed
EP-2049071-A2 DELIVERY SYSTEM AND METHOD OF MANUFACTURING THE SAME Amcol International Corporation (US) 2009-04-22 EP claimed
EP-1550435-B1 Deodorizing oil-in-water emulsion comprising a mixture of alkylpolyglycoside and fatty alcohol and a non ionic associative polyether polyurethane OREAL (FR) 2008-10-22 EP claimed
WO-2008013757-A2 DELIVERY SYSTEM AND METHOD OF MANUFACTURING THE SAME AMCOL INTERNATIONAL CORPORATION (US) 2008-01-31 WO claimed
US-20070044729-A1 AMUSEMENT ARTICLES POSSESSING MICROBE-INHIBITING PROPERTIES SEEFAR TECHNOLOGIES, INCORPORATED (US) 2007-03-01 US claimed
EP-1140033-B1 IMPROVED CONTROLLED RELEASE COMPOSITIONS AMCOL INTERNATIONAL CORP (US) 2005-10-12 EP claimed
US-6924326-B2 Method and formulation using passive electrostaticity for improving filter performance MAINSTREAM ENGINEERING CORPORATION (US) 2005-08-02 US claimed
US-20030032694-A1 Method and formulation using passive electrostaticity for improving filter performance MAINSTREAM ENGINEERING CORPORATION 2003-02-13 US claimed
US-5441742-A Cellular cellulosic material containing a biocide agent and process for preparing same FINANCIERE ELYSEES BALZAC (FR) 1995-08-15 US claimed
EP-0617074-A1 Alveolar cellulose material containing a biocide FINANCIERE ELYSEES BALZAC (FR) 1994-09-28 EP claimed
EP-4527370-A1 DERMATOLOGICAL AND COSMETIC COMPOSITION, IN PARTICULAR FOR TREATING HYPERPIGMENTATION AND OF RELATED SKIN IRRITATIONS FB Dermo srl (IT) 2025-03-26 EP disclosed
EP-4523699-A1 ANTI-INFLAMMATORY DERMATOLOGICAL COMPOSITION COMPRISING GLYCEROPHOSPHOINOSITOL, A LACTOFERRIN HYDROLYSATE AND A CANNABINOID, IN PARTICULAR FOR TREATING SEBORRHEIC DERMATITIS FB Dermo srl (IT) 2025-03-19 EP disclosed
US-20240041739-A1 BIOPHOTONIC COMPOSITIONS AND METHODS FOR PROVIDING BIOPHOTONIC TREATMENT KLOX TECHNOLOGIES INC. (CA) 2024-02-08 US disclosed
EP-3305279-B1 ULTRAVIOLET RADIATION ABSORBING POLYMER COMPOSITION JOHNSON & JOHNSON CONSUMER INC (US) 2021-04-07 EP disclosed
US-4626529-A AMINE-NEUTRALIZED ANIONIC SURFACTANT L'OREAL (FR) 1986-12-02 US disclosed
US-4471871-A Packaged dry-to-the-touch article and method of packaging the article LEVER BROTHERS COMPANY (US) 1984-09-18 US disclosed
EP-0109275-A2 Animal litter composition THE PROCTER & GAMBLE COMPANY (US) 1984-05-23 EP disclosed
US-4376789-A FOR COSMETICS GRILLO-WERKE AG (DE) 1983-03-15 US disclosed
US-4111844-A 2,4,4'-TRICHLORO-2'-HYDROXY-DIPHENYL ETHER, ANIONIC SURFACTANT, WATER CIBA-GEIGY CORPORATION (US) 1978-09-05 US disclosed