Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 14/20 | 1.00 |
| ▸ | FEN1 | P39748 | 14/20 | 1.00 |
| ▸ | ERCC4 | Q92889 | 14/20 | 1.00 |
| ▸ | DNASE1 | P24855 | 2/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13174730 | 0.83 | ERCC1 (0.70) | ERCC1FEN1ERCC4DNASE1 | |
| SCHEMBL6666990 | 0.80 | ERCC1 (0.66) | ERCC1FEN1ERCC4DNASE1 | |
| SCHEMBL6620626 | 0.77 | ERCC1 (0.68) | ERCC1FEN1ERCC4DNASE1 | |
| SCHEMBL6621889 | 0.77 | ERCC1 (0.62) | ERCC1FEN1ERCC4DNASE1 | |
| Hydrochloric Acid SCHEMBL6666184 | 0.77 | ERCC1 (0.62) | ERCC1FEN1ERCC4DNASE1 | |
| SCHEMBL6620564 | 0.76 | ERCC1 (0.61) | ERCC1FEN1ERCC4DNASE1 | |
| SCHEMBL4033473 | 0.75 | ERCC1 (0.60) | ERCC1FEN1ERCC4DNASE1 | |
| SCHEMBL3833902 | 0.75 | ERCC1 (0.60) | ERCC1FEN1ERCC4DNASE1 | |
| SCHEMBL15592592 | 0.74 | ERCC1 (0.68) | ERCC1FEN1ERCC4 | |
| SCHEMBL6619853 | 0.74 | ERCC1 (0.64) | ERCC1FEN1ERCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1470113-A1 | PYRIMIDINONE VIRAL POLYMERASE INHIBITORS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) | 2004-10-27 | — | — | EP | disclosed |
| WO-2003062211-A1 | PYRIMIDINONE VIRAL POLYMERASE INHIBITORS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2003-07-31 | — | — | WO | disclosed |