Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 8/20 | 0.60 |
| ▸ | FEN1 | P39748 | 8/20 | 0.60 |
| ▸ | ERCC4 | Q92889 | 8/20 | 0.60 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.44 |
| ▸ | DNASE1 | P24855 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6666184 | 0.81 | ERCC1 (0.62) | ERCC1FEN1ERCC4RNASEH1DNASE1 | |
| SCHEMBL6621889 | 0.81 | ERCC1 (0.62) | ERCC1FEN1ERCC4RNASEH1DNASE1 | |
| SCHEMBL6620564 | 0.81 | ERCC1 (0.61) | ERCC1FEN1ERCC4RNASEH1DNASE1 | |
| SCHEMBL13646996 | 0.78 | ALDH1A1 (0.40) | ERCC1FEN1ERCC4 | |
| SCHEMBL4028581 | 0.76 | ERCC1 (0.44) | ERCC1FEN1ERCC4RNASEH1 | |
| SCHEMBL6666990 | 0.75 | ERCC1 (0.66) | ERCC1FEN1ERCC4RNASEH1DNASE1 | |
| SCHEMBL6656091 | 0.75 | ERCC1 (1.00) | ERCC1FEN1ERCC4DNASE1 | |
| SCHEMBL6620626 | 0.72 | ERCC1 (0.68) | ERCC1FEN1ERCC4RNASEH1DNASE1 | |
| SCHEMBL6620304 | 0.72 | ERCC1 (0.53) | ERCC1FEN1ERCC4RNASEH1DNASE1 | |
| SCHEMBL13218191 | 0.69 | ERCC1 (0.76) | ERCC1FEN1ERCC4RNASEH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1470113-B1 | PYRIMIDINONE VIRAL POLYMERASE INHIBITORS | ANGELETTI P IST RICHERCHE BIO (IT) | 2009-01-07 | — | — | EP | disclosed |
| EP-1470113-A1 | PYRIMIDINONE VIRAL POLYMERASE INHIBITORS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) | 2004-10-27 | — | — | EP | disclosed |
| WO-2003062211-A1 | PYRIMIDINONE VIRAL POLYMERASE INHIBITORS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2003-07-31 | — | — | WO | disclosed |