Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC13A5 | Q86YT5 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | ESRRG | P62508 | 5/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ESRRB | O95718 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL589181 | 0.86 | SMN1; SMN2 (0.49) | LMNAMAPTSMN1; SMN2MMP8MEN1 | |
| SCHEMBL7617566 | 0.84 | MMP8 (0.61) | MAPTSMN1; SMN2MMP8MEN1ALDH1A1 | |
| SCHEMBL7622533 | 0.80 | MMP8 (0.57) | MAPTSMN1; SMN2MMP8ALDH1A1HDAC3 | |
| SCHEMBL5802443 | 0.80 | MMP8 (0.57) | SLC13A5LMNAMAPTSMN1; SMN2MMP8 | |
| SCHEMBL591080 | 0.79 | SMN1; SMN2 (0.46) | SLC13A5LMNAMAPTSMN1; SMN2MMP8 | |
| SCHEMBL31001663 | 0.78 | CYP4F2 (0.51) | SLC13A5MMP8MEN1ALDH1A1KMT2A | |
| SCHEMBL7713930 | 0.78 | MMP8 (0.58) | MAPTSMN1; SMN2MMP8MEN1ALDH1A1 | |
| SCHEMBL20521928 | 0.78 | LMNA (0.48) | LMNAMAPTSMN1; SMN2MMP8NR1H4 | |
| SCHEMBL4888029 | 0.78 | CYP4F2 (0.68) | SLC13A5LMNAMAPTSMN1; SMN2NR1H4 | |
| SCHEMBL7714028 | 0.76 | FFAR1 (0.55) | LMNAMAPTMMP8NR1H4EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1440976-A1 | Modified aminoacids, pharmaceuticals containing these compounds and method for their production | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2004-07-28 | — | — | EP | disclosed |