SCHEMBL6656563

SCHEMBL6656563

CC1(C)CN(Cc2ccccc2)C(C)(C)O1

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.45
MEN1 O00255 1/20 0.41
TSHR P16473 1/20 0.41
KMT2A Q03164 1/20 0.41
ELANE P08246 2/20 0.41
SIGMAR1 Q99720 1/20 0.39
CTSG P08311 1/20 0.39
PRTN3 P24158 1/20 0.39
AMPD2 Q01433 2/20 0.38
MC4R P32245 1/20 0.38
NTRK1 P04629 1/20 0.37
LMNA P02545 1/20 0.37
POLB P06746 1/20 0.37
ALDH1A1 P00352 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
ACHE P22303 1/20 0.36
CYP3A4 P08684 1/20 0.35
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2074248 0.78 GAA (0.61) GAAMEN1TSHRKMT2AELANE
SCHEMBL17700194 0.77 GAA (0.53) GAAMEN1TSHRKMT2AELANE
SCHEMBL26469162 0.71 SIGMAR1 (0.44) GAAMEN1TSHRKMT2AELANE
SCHEMBL16400295 0.71 MEN1 (0.39) GAAMEN1TSHRKMT2AELANE
SCHEMBL16400528 0.70 MEN1 (0.38) GAAMEN1TSHRKMT2AELANE
SCHEMBL12772472 0.70 GAA (0.51) GAAMEN1TSHRKMT2AELANE
SCHEMBL16400527 0.69 GAA (0.40) GAAMEN1TSHRKMT2AELANE
SCHEMBL26981274 0.69 ELANE (0.50) GAAMEN1KMT2AELANESIGMAR1
SCHEMBL28058814 0.69 GAA (0.46) GAAMEN1TSHRKMT2AELANE
SCHEMBL2075027 0.69 GAA (0.50) GAAMEN1TSHRKMT2ASIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6271387-B1 Process for producing 1,3-oxazolidine derivatives DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2001-08-07 US claimed
EP-1026161-B1 Process for producing 1,3-oxazolidine derivatives DAICEL CHEM (JP) 2004-07-21 EP disclosed
US-6271387-B1 Process for producing 1,3-oxazolidine derivatives DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2001-08-07 US disclosed
EP-1026161-A1 Process for producing 1,3-oxazolidine derivatives Daicel Chemical Industries, Ltd. (JP) 2000-08-09 EP disclosed