Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.44 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CTSG | P08311 | 1/20 | 0.39 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16673137 | 0.79 | SIGMAR1 (0.38) | SIGMAR1MC4RGAAELANELMNA | |
| SCHEMBL6132960 | 0.76 | JAK2 (0.44) | SIGMAR1MC4RGAAELANELMNA | |
| SCHEMBL18096014 | 0.73 | GAA (0.44) | SIGMAR1MC4RGAAELANECTSG | |
| SCHEMBL12626083 | 0.73 | CYP3A4 (0.53) | SIGMAR1POLBCYP2D6CYP3A4HSD17B10 | |
| SCHEMBL17700194 | 0.72 | GAA (0.53) | SIGMAR1MC4RGAAELANELMNA | |
| SCHEMBL2073777 | 0.72 | SIGMAR1 (0.50) | SIGMAR1MC4RGAALMNAPOLB | |
| SCHEMBL12625885 | 0.72 | TSHR (0.51) | SIGMAR1CYP2D6CYP3A4HSD17B10MEN1 | |
| SCHEMBL6656563 | 0.71 | GAA (0.45) | SIGMAR1MC4RGAAELANELMNA | |
| SCHEMBL6133227 | 0.71 | ALDH1A1 (0.39) | SIGMAR1MC4RGAAPOLBMEN1 | |
| SCHEMBL7371862 | 0.71 | GAA (0.49) | SIGMAR1MC4RGAALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023072143-A1 | CAMPTOTHECIN DERIVATIVE INTERMEDIATE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海弼领生物技术有限公司 | 2023-05-04 | — | — | WO | disclosed |