Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | TTR | P02766 | 1/20 | 0.53 |
| ▸ | DPP4 | P27487 | 1/20 | 0.53 |
| ▸ | FDPS | P14324 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | BACE1 | P56817 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9599975 | 0.89 | KDM4E (0.74) | KDM4EALDH1A1SMN1; SMN2TTRDPP4 | |
| SCHEMBL9599969 | 0.89 | KDM4E (0.74) | KDM4EALDH1A1SMN1; SMN2TTRDPP4 | |
| SCHEMBL1210329 | 0.86 | MAOB (0.60) | KDM4EALDH1A1SMN1; SMN2TTRDPP4 | |
| SCHEMBL29421074 | 0.86 | MAOB (0.60) | KDM4EALDH1A1SMN1; SMN2TTRDPP4 | |
| SCHEMBL1210331 | 0.86 | MAOB (0.60) | KDM4EALDH1A1SMN1; SMN2TTRDPP4 | |
| SCHEMBL7222278 | 0.85 | KDM4E (0.60) | KDM4EALDH1A1SMN1; SMN2TTRDPP4 | |
| SCHEMBL7222274 | 0.85 | KDM4E (0.60) | KDM4EALDH1A1SMN1; SMN2TTRDPP4 | |
| SCHEMBL11684172 | 0.84 | KDM4E (0.59) | KDM4EALDH1A1SMN1; SMN2TTRDPP4 | |
| SCHEMBL28316404 | 0.84 | KDM4E (0.59) | KDM4EALDH1A1SMN1; SMN2TTRDPP4 | |
| SCHEMBL11684170 | 0.84 | KDM4E (0.59) | KDM4EALDH1A1SMN1; SMN2TTRDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040254241-A1 | Enzyme inhibitor; cognition activators | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2004-12-16 | — | — | US | disclosed |
| EP-1431280-A1 | ARYL SULFAMATE DERIVATIVES | Kyowa Hakko Kogyo Co., Ltd (JP) | 2004-06-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040254241-A1 | Enzyme inhibitor; cognition activators | SULT1A1, STS, CYP26A1 | KDM4E 3017/4885ALDH1A1 1187/4885SMN1; SMN2 3118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.