Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL6663960 | 0.92 | MEN1 (0.56) | MEN1KMT2A | |
| SCHEMBL1133203 | 0.92 | MEN1 (0.62) | MEN1KMT2ACHRNB2CHRNA4 | |
| SCHEMBL6661062 | 0.83 | MEN1 (0.48) | MEN1KMT2A | |
| SCHEMBL17426972 | 0.81 | MEN1 (0.53) | MEN1KMT2A | |
| SCHEMBL12861623 | 0.79 | MEN1 (0.50) | MEN1KMT2A | |
| SCHEMBL13333617 | 0.79 | MEN1 (0.50) | MEN1KMT2A | |
| SCHEMBL17426956 | 0.79 | MEN1 (0.50) | MEN1KMT2A | |
| Bromide SCHEMBL6659569 | 0.79 | MEN1 (0.50) | MEN1KMT2A | |
| SCHEMBL17426960 | 0.79 | MEN1 (0.50) | MEN1KMT2A | |
| SCHEMBL1314528 | 0.77 | MEN1 (0.56) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1160267-B1 | CATALYST FOR OXIDATIVE POLYMERIZATION OF FLUOROPHENOL, METHOD OF OXIDATIVE POLYMERIZATION OF FLUOROPHENOL, AND POLY(OXYFLUOROPHENYLENE) DERIVATIVE | JAPAN SCIENCE & TECH CORP (JP) | 2004-08-04 | — | — | EP | disclosed |