SCHEMBL6656906

SCHEMBL6656906

COC(=O)c1ccc(CCC(O)CCc2ccc(C(=O)OC)cc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4A11 Q02928 3/20 0.62
CYP4F2 P78329 2/20 0.60
LOXL2 Q9Y4K0 1/20 0.58
ALDH1A1 P00352 1/20 0.51
TP53 P04637 1/20 0.51
CYP1A2 P05177 1/20 0.51
CYP3A4 P08684 1/20 0.51
CYP2C9 P11712 1/20 0.51
HPGD P15428 1/20 0.51
ALOX15 P16050 1/20 0.51
ALOX12 P18054 1/20 0.51
CYP2C19 P33261 1/20 0.51
CKS1B P61024 1/20 0.51
SKP2 Q13309 1/20 0.51
HIF1A Q16665 1/20 0.51
HSD17B10 Q99714 1/20 0.51
CA1 P00915 3/20 0.50
CA2 P00918 3/20 0.50
MAPT P10636 2/20 0.50
TDP1 Q9NUW8 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8746160 0.92 CYP4A11 (0.57) CYP4A11CYP4F2LOXL2ALDH1A1TP53
SCHEMBL29055656 0.88 CYP4A11 (0.60) CYP4A11CYP4F2LOXL2ALDH1A1TP53
SCHEMBL13681171 0.86 CYP4A11 (0.58) CYP4A11CYP4F2LOXL2ALDH1A1TP53
SCHEMBL8293519 0.86 CYP4A11 (0.62) CYP4A11CYP4F2LOXL2ALDH1A1TP53
SCHEMBL27660158 0.85 CYP4A11 (0.50) CYP4A11CYP4F2LOXL2ALDH1A1TP53
SCHEMBL70185 0.85 CYP4A11 (0.75) CYP4A11CYP4F2LOXL2ALDH1A1TP53
SCHEMBL3485224 0.84 CYP4A11 (0.60) CYP4A11CYP4F2LOXL2ALDH1A1TP53
SCHEMBL31753280 0.84 CYP4A11 (0.60) CYP4A11CYP4F2LOXL2ALDH1A1TP53
SCHEMBL7822297 0.83 CYP4A11 (0.55) CYP4A11CYP4F2LOXL2ALDH1A1TP53
SCHEMBL10565182 0.83 LOXL2 (0.59) CYP4A11CYP4F2LOXL2ALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0758350-B1 PHOTODEGRADABLE POLYESTERS EASTMAN CHEM CO (US) 1999-08-18 EP claimed
EP-0758350-A1 PHOTODEGRADABLE POLYESTERS EASTMAN CHEMICAL COMPANY (US) 1997-02-19 EP claimed
WO-1995030701-A1 PHOTODEGRADABLE POLYESTERS EASTMAN CHEMICAL COMPANY (US) 1995-11-16 WO claimed
US-5434236-A Packaging films WHITE ALAN W (US) 1995-07-18 US claimed
EP-1140787-B1 CROSSLINKERS BASED ON DIBENZALACETONE DERIVATIVES EASTMAN CHEM CO (US) 2004-07-28 EP disclosed
US-6194615-B1 USEFUL AS CROSSLINKERS IN COATINGS APPLICATIONS EASTMAN CHEMICAL COMPANY 2001-02-27 US disclosed
EP-0758350-B1 PHOTODEGRADABLE POLYESTERS EASTMAN CHEM CO (US) 1999-08-18 EP disclosed
EP-0758350-A1 PHOTODEGRADABLE POLYESTERS EASTMAN CHEMICAL COMPANY (US) 1997-02-19 EP disclosed
WO-1995030701-A1 PHOTODEGRADABLE POLYESTERS EASTMAN CHEMICAL COMPANY (US) 1995-11-16 WO disclosed
US-5434236-A Packaging films WHITE ALAN W (US) 1995-07-18 US disclosed
US-5395692-A Photodegradable polyesters EASTMAN CHEMICAL COMPANY (US) 1995-03-07 US disclosed
US-5187304-A 1,5-Bis/4-carboxycyclohexyl/-3-pentanol and derivatives as monomers for polyester coatings or molding materials EASTMAN KODAK COMPANY (US) 1993-02-16 US disclosed
US-5144003-A Curable copolymers containing 1,5-bis(4-carboxycyclohexyl)-3-pentanol monomer; castings and moldings EASTMAN KODAK COMPANY (US) 1992-09-01 US disclosed
US-5025086-A Hardness, flexibility EASTMAN KODAK COMPANY (US) 1991-06-18 US disclosed
US-4965399-A 1,5-diaryl-3-pentanol compounds and processes for the preparation thereof EASTMAN KODAK COMPANY (US) 1990-10-23 US disclosed
US-4923958-A Novel unsaturated polyesters EASTMAN KODAK COMPANY (US) 1990-05-08 US disclosed