Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.32 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7050222 | 0.83 | GPR3 (0.35) | GPR3HTR2AALDH1A1POLBSLC22A2 | |
| SCHEMBL5980986 | 0.79 | GPR3 (0.39) | GPR3HTR2AALDH1A1CHRM2HTR1A | |
| Hydrochloric Acid SCHEMBL7049650 | 0.79 | CYP19A1 (0.34) | GPR3HTR2AADRA2AADRA1APOLB | |
| Hydrochloric Acid SCHEMBL7118139 | 0.79 | GPR3 (0.33) | GPR3HTR2APOLBSLC22A2SLC22A3 | |
| Hydrochloric Acid SCHEMBL7056957 | 0.79 | GPR3 (0.33) | GPR3HTR2APOLBSLC22A2SLC22A3 | |
| Hydrochloric Acid SCHEMBL7049642 | 0.79 | GPR3 (0.33) | GPR3HTR2APOLBSLC22A2SLC22A3 | |
| Hydrochloric Acid SCHEMBL7048575 | 0.79 | CYP19A1 (0.34) | GPR3HTR2AADRA2AADRA1APOLB | |
| SCHEMBL8970979 | 0.79 | GPR3 (0.38) | GPR3HTR2AALDH1A1CHRM2HTR1A | |
| Hydrochloric Acid SCHEMBL7118144 | 0.79 | CYP19A1 (0.34) | GPR3HTR2AADRA2AADRA1APOLB | |
| Hydrochloric Acid SCHEMBL7056966 | 0.79 | CYP19A1 (0.34) | GPR3HTR2AADRA2AADRA1APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5492974-A | Process for preparing polymer bound metallocenes | PHILLIPS PETROLEUM COMPANY (US) | 1996-02-20 | — | — | US | claimed |
| EP-0690076-A1 | Polymer bound ligands, polymer bound metallocenes, catalyst systems, preparation, and use | PHILLIPS PETROLEUM COMPANY (US) | 1996-01-03 | — | — | EP | claimed |
| US-5473020-A | Polymer bound ligands, polymer bound metallocenes, catalyst systems, preparation, and use | PHILLIPS PETROLEUM COMPANY (US) | 1995-12-05 | — | — | US | claimed |
| EP-1046642-B1 | Process for preparation of silyl-bridged fluorenyl-cyclopentadienyl ligands and silyl-bridged fluorenyl-cyclopentadienyl metallocenes | BASELL POLYOLEFINE GMBH (DE) | 2004-06-30 | — | — | EP | disclosed |
| EP-0628577-B2 | Silyl bridged metallocenes and use thereof | PHILLIPS PETROLEUM CO (US) | 2002-10-09 | — | — | EP | disclosed |
| US-6346635-B1 | FORMING A COMPLEX, DEPROTINATION, SILATION AND COMPLEXING | BASELL POLYOLEFINE GMBH (DE) | 2002-02-12 | — | — | US | disclosed |
| US-6297333-B1 | METALLOCENE TRANSITION METAL COMPOUND HAVING AN INDENYL GROUP AND A FLUORENYL GROUP AS LIGANDS, SPECIFIC SUBSTITUENT ON A SPECIFIC POSITION OF THE INDENYL GROUP GIVES HIGH MOLECULAR WEIGHT AND HIGH ACTIVITY | MITSUI CHEMICALS INC (JP) | 2001-10-02 | — | — | US | disclosed |
| EP-1046642-A2 | Process for preparation of silyl-bridged fluorenyl-cyclopentadienyl ligands and silyl-bridged fluorenyl-cyclopentadienyl metallocenes | TARGOR GmbH (DE) | 2000-10-25 | — | — | EP | disclosed |
| US-6004897-A | TRANSITION METAL INDENE-FLUORINE COMPLEX COORDINATION CATALYST WITH ORGANOALUMINUM AND ALUMOXANE COMPOUNDS | MITSUI CHEMICALS, INC. (JP) | 1999-12-21 | — | — | US | disclosed |
| EP-0628577-B1 | Silyl bridged metallocenes and use thereof | PHILLIPS PETROLEUM CO (US) | 1999-03-03 | — | — | EP | disclosed |
| EP-0875517-A1 | Novel homopolymers of propylene exhibiting more than 50% syndiotacticity and more than 50 wt-% xylene solubles | PHILLIPS PETROLEUM COMPANY (US) | 1998-11-04 | — | — | EP | disclosed |
| US-5492974-A | Process for preparing polymer bound metallocenes | PHILLIPS PETROLEUM COMPANY (US) | 1996-02-20 | — | — | US | disclosed |
| US-5492978-A | Process for preparing catalyst system | PHILLIPS PETROLEUM COMPANY (US) | 1996-02-20 | — | — | US | disclosed |
| US-5492973-A | Polymer bound ligands | PHILLIPS PETROLEUM COMPANY (US) | 1996-02-20 | — | — | US | disclosed |
| EP-0690076-A1 | Polymer bound ligands, polymer bound metallocenes, catalyst systems, preparation, and use | PHILLIPS PETROLEUM COMPANY (US) | 1996-01-03 | — | — | EP | disclosed |
| US-5473020-A | Polymer bound ligands, polymer bound metallocenes, catalyst systems, preparation, and use | PHILLIPS PETROLEUM COMPANY (US) | 1995-12-05 | — | — | US | disclosed |
| US-5459218-A | Containing fluorene ring | PHILLIPS PETROLEUM COMPANY (US) | 1995-10-17 | — | — | US | disclosed |
| US-5401817-A | Syndiotactic polypropylene | PHILLIPS PETROLEUM COMPANY (US) | 1995-03-28 | — | — | US | disclosed |
| US-5393911-A | Cyclopentadiene type compounds and method for making | PHILLIPS PETROLEUM COMPANY (US) | 1995-02-28 | — | — | US | disclosed |
| EP-0628577-A2 | Silyl bridged metallocenes and use thereof | PHILLIPS PETROLEUM COMPANY (US) | 1994-12-14 | — | — | EP | disclosed |