SCHEMBL6656944

SCHEMBL6656944

CCCCC(CC)Cc1ccc2cc3cc4cc5ccccc5cc4cc3cc2c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BDKRB2 P30411 3/20 0.47
HTR2A P28223 1/20 0.46
HTR2C P28335 1/20 0.46
HTR2B P41595 1/20 0.46
CYP1A2 P05177 1/20 0.44
CYP2A6 P11509 1/20 0.44
MME P08473 2/20 0.40
SIGMAR1 Q99720 2/20 0.40
ACE P12821 1/20 0.40
CPA1 P15085 1/20 0.40
ACE2 Q9BYF1 1/20 0.40
BCHE P06276 1/20 0.40
ALDH1A1 P00352 2/20 0.39
CA2 P00918 1/20 0.39
CYP3A4 P08684 1/20 0.39
KDM4E B2RXH2 1/20 0.38
NR3C1 P04150 1/20 0.38
PGR P06401 1/20 0.38
NR3C2 P08235 1/20 0.38
MC4R P32245 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15301082 1.00 BDKRB2 (0.47) BDKRB2HTR2AHTR2CHTR2BCYP1A2
SCHEMBL3731371 0.95 BDKRB2 (0.51) BDKRB2HTR2AHTR2CHTR2BCYP1A2
SCHEMBL3723663 0.95 BDKRB2 (0.51) BDKRB2HTR2AHTR2CHTR2BCYP1A2
SCHEMBL20342362 0.87 BDKRB2 (0.40) BDKRB2HTR2AHTR2CHTR2BCYP1A2
SCHEMBL20730395 0.85 BDKRB2 (0.38) BDKRB2HTR2AHTR2CHTR2BCYP1A2
SCHEMBL14353644 0.82 BDKRB2 (0.56) BDKRB2HTR2AHTR2CHTR2BCYP1A2
SCHEMBL28163233 0.82 BDKRB2 (0.56) BDKRB2HTR2AHTR2CHTR2BCYP1A2
SCHEMBL28033428 0.82 BDKRB2 (0.45) BDKRB2CYP1A2CYP2A6CYP3A4KDM4E
SCHEMBL16807625 0.80 BDKRB2 (0.41) BDKRB2HTR2AHTR2CHTR2BALDH1A1
SCHEMBL17489609 0.80 KIF11 (0.39) BDKRB2HTR2AHTR2CHTR2BCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1592729-A Process for preparing pentacene derivatives 3M INNOVATIVE PROPERTIES CO (US) 2005-03-09 CN disclosed
CN-1582506-A Substituted pentacene semiconductors 3M INNOVATIVE PROPERTIES CO (US) 2005-02-16 CN disclosed
EP-1433211-A2 SUBSTITUTED PENTACENE SEMICONDUCTORS 3M Innovative Properties Company (US) 2004-06-30 EP disclosed
EP-1430008-A2 PROCESS FOR PREPARING PENTACENE DERIVATIVES 3M Innovative Properties Company (US) 2004-06-23 EP disclosed
WO-2003028125-A2 SUBSTITUTED PENTACENE SEMICONDUCTORS 3M INNOVATIVE PROPERTIES COMPANY (US) 2003-04-03 WO disclosed
WO-2003027050-A2 PROCESS FOR PREPARING PENTACENE DERIVATIVES 3M INNOVATIVE PROPERTIES COMPANY (US) 2003-04-03 WO disclosed