Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CEL | P19835 | 7/20 | 1.00 |
| ▸ | CTRC | Q99895 | 2/20 | 0.45 |
| ▸ | DAO | P14920 | 3/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13059860 | 0.69 | CEL (0.53) | CELRAB9AL3MBTL1RECQL | |
| SCHEMBL1733071 | 0.69 | CEL (0.51) | CELRAB9AL3MBTL1TSHR | |
| SCHEMBL16191584 | 0.66 | CEL (0.49) | CELDAORAB9AL3MBTL1SMN1; SMN2 | |
| SCHEMBL21622788 | 0.65 | MAOB (0.55) | CELRAB9A | |
| SCHEMBL19465402 | 0.65 | BCHE (0.49) | CELRAB9AL3MBTL1 | |
| SCHEMBL22777725 | 0.64 | CEL (0.47) | CELRAB9A | |
| SCHEMBL1732699 | 0.63 | CEL (0.46) | CELRAB9AL3MBTL1TSHR | |
| SCHEMBL9406420 | 0.63 | CEL (0.46) | CELDAORAB9AL3MBTL1 | |
| SCHEMBL16191075 | 0.63 | HTR2A (0.58) | CELSMN1; SMN2 | |
| SCHEMBL20837584 | 0.62 | CEL (0.46) | CELDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1323715-B1 | Inhibitors of cholesterol esterase | UNIV NEW MEXICO (US) | 2004-06-30 | — | — | EP | disclosed |
| EP-0975617-B1 | INHIBITORS OF CHOLESTEROL ESTERASE | UNIV NEW MEXICO (US) | 2003-11-05 | — | — | EP | disclosed |
| EP-1323715-A1 | Inhibitors of cholesterol esterase | The University of New Mexico (US) | 2003-07-02 | — | — | EP | disclosed |
| EP-0975617-A4 | INHIBITORS OF CHOLESTEROL ESTERASE | UNIV NEW MEXICO (US) | 2000-09-13 | — | — | EP | disclosed |
| US-6114545-A | Inhibitors of cholesterol esterase | UNIVERSITY OF NEW MEXICO (US) | 2000-09-05 | — | — | US | disclosed |
| US-6034255-A | Inhibitors of cholesterol esterase | UNIVERSITY OF NEW MEXICO (US) | 2000-03-07 | — | — | US | disclosed |
| EP-0975617-A1 | INHIBITORS OF CHOLESTEROL ESTERASE | The University of New Mexico (US) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998046585-A1 | INHIBITORS OF CHOLESTEROL ESTERASE | THE UNIVERSITY OF NEW MEXICO (US) | 1998-10-22 | — | — | WO | disclosed |