Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 4/20 | 0.36 |
| ▸ | THRB | P10828 | 4/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.35 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9809630 | 0.78 | THRA (0.46) | THRATHRBGPR84NR5A1PLA2G2A | |
| SCHEMBL26278000 | 0.78 | THRA (0.46) | THRATHRBGPR84NR5A1PLA2G2A | |
| SCHEMBL9809613 | 0.78 | THRA (0.46) | THRATHRBGPR84NR5A1PLA2G2A | |
| SCHEMBL26278001 | 0.78 | THRA (0.46) | THRATHRBGPR84NR5A1PLA2G2A | |
| SCHEMBL9809623 | 0.78 | THRA (0.46) | THRATHRBGPR84NR5A1PLA2G2A | |
| SCHEMBL6658770 | 0.78 | THRA (0.46) | THRATHRBGPR84NR5A1PLA2G2A | |
| SCHEMBL9809602 | 0.76 | THRA (0.44) | THRATHRBGPR84NR5A1PLA2G2A | |
| SCHEMBL25025146 | 0.73 | POLB (0.41) | GPR84TSHRPOLBGAA | |
| SCHEMBL31163657 | 0.73 | POLB (0.41) | GPR84TSHRPOLBGAA | |
| SCHEMBL22301648 | 0.73 | POLB (0.41) | GPR84TSHRPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1438328-A1 | NOVEL METHOD FOR RECOVERY OF SQUARIC ACID MONO ESTERS IN BIOCONJUGATION CHEMISTRY | Lundonia Biotech AB (SE) | 2004-07-21 | — | — | EP | disclosed |
| WO-2003035672-A1 | NOVEL METHOD FOR RECOVERY OF SQUARIC ACID MONO ESTERS IN BIOCONJUGATION CHEMISTRY | LUNDONIA BIOTECH AB (SE) | 2003-05-01 | — | — | WO | disclosed |