Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 11/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5746983 | 0.73 | HTR7 (0.47) | LTA4H | |
| SCHEMBL5746592 | 0.72 | HTR7 (0.48) | LTA4H | |
| SCHEMBL5747302 | 0.70 | HTR7 (0.43) | LTA4H | |
| SCHEMBL21121296 | 0.69 | ESR1 (0.66) | LTA4HACHEESR1KCNH2 | |
| SCHEMBL4541283 | 0.68 | NPC1 (0.41) | LTA4HACHEESR1 | |
| SCHEMBL30117493 | 0.68 | MEN1 (0.55) | MEN1MAPTKMT2ALTA4HACHE | |
| SCHEMBL31033194 | 0.68 | MEN1 (0.86) | MEN1MAPTKMT2ALTA4HACHE | |
| SCHEMBL6575812 | 0.68 | MEN1 (0.86) | MEN1MAPTKMT2ALTA4HACHE | |
| SCHEMBL4539823 | 0.67 | NPC1 (0.40) | LTA4HACHEESR1 | |
| SCHEMBL7134330 | 0.67 | SRC (0.46) | LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1482931-A2 | MONO- AND BICYCLIC AZOLE DERIVATIVES THAT INHIBIT THE INTERACTION OF LIGANDS WITH RAGE | Transtech Pharma, Inc. (US) | 2004-12-08 | — | — | EP | disclosed |
| WO-2003075921-A2 | MONO- AND BICYCLIC AZOLE DERIVATIVES THAT INHIBIT THE INTERACTION OF LIGANDS WITH RAGE | TRANSTECH PHARMA, INC. (US) | 2003-09-18 | — | — | WO | disclosed |